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Late-onset leukoencephalopathy with cerebral calcifications and cysts: case report and review of the literature

Overview of attention for article published in BMC Neurology, February 2016
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Title
Late-onset leukoencephalopathy with cerebral calcifications and cysts: case report and review of the literature
Published in
BMC Neurology, February 2016
DOI 10.1186/s12883-016-0543-1
Pubmed ID
Authors

C. Stephani, S. Pfeifenbring, A. Mohr, C. Stadelmann

Abstract

Leukoencephalopathy with calcifications and cysts (LCC or Labrune disease) is a relatively recently defined and exceptionally rare disease in which parenchymal cysts and calcifications within a widespread leukoencephalopathy can cause a broad spectrum of neurological symptoms. The cause of the disease is unknown. Manifestation is usually in childhood or adolescence, while onset in adulthood has been described in 19 cases. Here we report a case of an adult-onset LCC of a Caucasian woman who became symptomatic at age 70 as confirmed by typical neuroimaging and neuropathological findings. After resection of left mesioparietal space-occupying cystic brain tissue the patient has so far remained clinically stable during one year of follow-up with a continuous treatment with glucocorticosteroids. To our knowledge this report of a patient who became symptomatic at age 70 represents the oldest age-at-onset case of LCC described so far.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 20%
Student > Postgraduate 2 20%
Other 1 10%
Student > Bachelor 1 10%
Lecturer > Senior Lecturer 1 10%
Other 3 30%
Readers by discipline Count As %
Medicine and Dentistry 6 60%
Agricultural and Biological Sciences 1 10%
Biochemistry, Genetics and Molecular Biology 1 10%
Neuroscience 1 10%
Unspecified 1 10%
Other 0 0%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2016.
All research outputs
#5,938,011
of 8,204,367 outputs
Outputs from BMC Neurology
#959
of 1,241 outputs
Outputs of similar age
#167,247
of 257,238 outputs
Outputs of similar age from BMC Neurology
#52
of 63 outputs
Altmetric has tracked 8,204,367 research outputs across all sources so far. This one is in the 24th percentile – i.e., 24% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,241 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
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