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Late-onset leukoencephalopathy with cerebral calcifications and cysts: case report and review of the literature

Overview of attention for article published in BMC Neurology, February 2016
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Title
Late-onset leukoencephalopathy with cerebral calcifications and cysts: case report and review of the literature
Published in
BMC Neurology, February 2016
DOI 10.1186/s12883-016-0543-1
Pubmed ID
Authors

C. Stephani, S. Pfeifenbring, A. Mohr, C. Stadelmann

Abstract

Leukoencephalopathy with calcifications and cysts (LCC or Labrune disease) is a relatively recently defined and exceptionally rare disease in which parenchymal cysts and calcifications within a widespread leukoencephalopathy can cause a broad spectrum of neurological symptoms. The cause of the disease is unknown. Manifestation is usually in childhood or adolescence, while onset in adulthood has been described in 19 cases. Here we report a case of an adult-onset LCC of a Caucasian woman who became symptomatic at age 70 as confirmed by typical neuroimaging and neuropathological findings. After resection of left mesioparietal space-occupying cystic brain tissue the patient has so far remained clinically stable during one year of follow-up with a continuous treatment with glucocorticosteroids. To our knowledge this report of a patient who became symptomatic at age 70 represents the oldest age-at-onset case of LCC described so far.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 22%
Other 4 15%
Student > Doctoral Student 3 11%
Professor 3 11%
Student > Postgraduate 2 7%
Other 5 19%
Unknown 4 15%
Readers by discipline Count As %
Medicine and Dentistry 12 44%
Neuroscience 6 22%
Nursing and Health Professions 2 7%
Agricultural and Biological Sciences 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 0 0%
Unknown 5 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2016.
All research outputs
#17,812,370
of 22,882,389 outputs
Outputs from BMC Neurology
#1,795
of 2,440 outputs
Outputs of similar age
#271,013
of 397,431 outputs
Outputs of similar age from BMC Neurology
#31
of 37 outputs
Altmetric has tracked 22,882,389 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,440 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 397,431 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.