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Improved weight management using genetic information to personalize a calorie controlled diet

Overview of attention for article published in Nutrition Journal, October 2007
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (82nd percentile)

Mentioned by

news
3 news outlets
blogs
2 blogs
twitter
14 tweeters
patent
1 patent
facebook
6 Facebook pages
video
1 video uploader

Citations

dimensions_citation
104 Dimensions

Readers on

mendeley
245 Mendeley
citeulike
1 CiteULike
Title
Improved weight management using genetic information to personalize a calorie controlled diet
Published in
Nutrition Journal, October 2007
DOI 10.1186/1475-2891-6-29
Pubmed ID
Authors

Ioannis Arkadianos, Ana M Valdes, Efstathios Marinos, Anna Florou, Rosalynn D Gill, Keith A Grimaldi

Abstract

Gene-environment studies demonstrate variability in nutrient requirements depending upon individual variations in genes affecting nutrient metabolism and transport. This study investigated whether the inclusion of genetic information to personalize a patient's diet (nutrigenetics) could improve long term weight management. Patients with a history of failures at weight loss were offered a nutrigenetic test screening 24 variants in 19 genes involved in metabolism. 50 patients were in the nutrigenetic group and 43 patients attending the same clinic were selected for comparison using algorithms to match the characteristics: age, sex, frequency of clinical visits and BMI at initial clinic visit. The second group of 43 patients did not receive a nutrigenetic test. BMI reduction at 100 and > 300 days and blood fasting glucose were measured. After 300 days of follow-up individuals in the nutrigenetic group were more likely to have maintained some weight loss (73%) than those in the comparison group (32%), resulting in an age and gender adjusted OR of 5.74 (95% CI 1.74-22.52). Average BMI reduction in the nutrigenetic group was 1.93 kg/m2(5.6% loss) vs. an average BMI gain of 0.51 kg/m2(2.2% gain) (p < 0.023). Among patients with a starting blood fasting glucose of > 100 mg/dL, 57% (17/30) of the nutrigenetic group but only 25% (4/16) of the non-tested group had levels reduced to < 100 mg/dL after > 90 days of weight management therapy (OR for lowering glucose to < 100 mg/dL due to diet = 1.98 95%CI 1.01, 3.87, p < 0.046). Addition of nutrigenetically tailored diets resulted in better compliance, longer-term BMI reduction and improvements in blood glucose levels.

Twitter Demographics

The data shown below were collected from the profiles of 14 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 245 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 <1%
Netherlands 1 <1%
Germany 1 <1%
Italy 1 <1%
Spain 1 <1%
Unknown 239 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 42 17%
Student > Bachelor 35 14%
Researcher 31 13%
Student > Ph. D. Student 29 12%
Other 26 11%
Other 40 16%
Unknown 42 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 48 20%
Medicine and Dentistry 47 19%
Nursing and Health Professions 22 9%
Biochemistry, Genetics and Molecular Biology 22 9%
Sports and Recreations 12 5%
Other 38 16%
Unknown 56 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 55. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2020.
All research outputs
#567,292
of 20,751,917 outputs
Outputs from Nutrition Journal
#171
of 1,374 outputs
Outputs of similar age
#5,387
of 287,388 outputs
Outputs of similar age from Nutrition Journal
#20
of 106 outputs
Altmetric has tracked 20,751,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,374 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 32.8. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,388 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.