↓ Skip to main content

Evaluation of the cytotoxic effect and antibacterial, antifungal, and antiviral activities of Hypericum triquetrifolium Turra essential oils from Tunisia

Overview of attention for article published in BMC Complementary and Alternative Medicine, January 2013
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

Mentioned by

blogs
1 blog
twitter
1 tweeter

Citations

dimensions_citation
14 Dimensions

Readers on

mendeley
42 Mendeley
Title
Evaluation of the cytotoxic effect and antibacterial, antifungal, and antiviral activities of Hypericum triquetrifolium Turra essential oils from Tunisia
Published in
BMC Complementary and Alternative Medicine, January 2013
DOI 10.1186/1472-6882-13-24
Pubmed ID
Authors

Zyed Rouis, Nabil Abid, Sadok Koudja, Thabet Yangui, Ameur Elaissi, Pier Luigi Cioni, Guido Flamini, Mahjoub Aouni

Abstract

ABSTRACT: BACKGROUND: A number of bio-active secondary metabolites have been identified and reported for several Hypericum species. Many studies have reported the potential use of the plant extracts against several pathogens. However, Hypericum triquetrifolium is one of the least studied species for its antimicrobial activity. The aim of the present study was to evaluate the cytotoxic effect of the essential oils of Hypericum triquetrifolium as well as their antimicrobial potential against coxsakievirus B3 and a range of bacterial and fungal strains. METHODS: The essential oils of Hypericum triquetrifolium harvested from five different Tunisian localities (Fondouk DJedid, Bou Arada, Bahra, Fernana and Dhrea Ben Jouder) were evaluated for their antimicrobial activities by micro-broth dilution methods against bacterial and fungal strains. In addition, the cytotoxic effect and the antiviral activity of these oils were carried out using Vero cell lines and coxsakievirus B3. RESULTS: The results showed a good antibacterial activities against a wide range of bacterial strains, MIC values ranging between 0.39-12.50 mg/ml and MBC values between 1.56-25.0 mg/ml. In addition, the essential oils showed promising antifungal activity with MIC values ranging between 0.39 mug/mL and 12.50 mug/mL; MFC values ranged between 3.12 mug/mL and 25.00 mug/mL; a significant anticandidal activity was noted (MIC values comprised between 0.39 mug/mL and 12.50 mug/mL). Although their low cytotoxic effect (CC50 ranged between 0.58 mg/mL and 12.00 mg/mL), the essential oils did not show antiviral activity against coxsakievirus B3. CONCLUSION: The essential oils obtained from Hypericum triquetrifolium can be used as antimicrobial agents and could be safe at non cytotoxic doses. As shown for the tested essential oils, comparative analysis need to be undertaken to better characterize also the antimicrobial activities of Hypericum triquetrifolium extracts with different solvents as well as their purified fractions and their pure secondary metabolites.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 2%
Morocco 1 2%
Cameroon 1 2%
Unknown 39 93%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 7 17%
Student > Bachelor 7 17%
Researcher 6 14%
Unspecified 4 10%
Student > Master 4 10%
Other 14 33%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 43%
Biochemistry, Genetics and Molecular Biology 5 12%
Unspecified 5 12%
Medicine and Dentistry 4 10%
Immunology and Microbiology 3 7%
Other 7 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 April 2016.
All research outputs
#1,140,736
of 12,373,386 outputs
Outputs from BMC Complementary and Alternative Medicine
#266
of 2,512 outputs
Outputs of similar age
#27,463
of 260,488 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#3
of 9 outputs
Altmetric has tracked 12,373,386 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,512 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 260,488 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.