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Adult reversal of cognitive phenotypes in neurodevelopmental disorders

Overview of attention for article published in Journal of Neurodevelopmental Disorders, June 2009
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (55th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
2 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
32 Dimensions

Readers on

mendeley
69 Mendeley
citeulike
1 CiteULike
Title
Adult reversal of cognitive phenotypes in neurodevelopmental disorders
Published in
Journal of Neurodevelopmental Disorders, June 2009
DOI 10.1007/s11689-009-9018-7
Pubmed ID
Authors

Alcino J. Silva, Dan Ehninger

Abstract

Recent findings in mice suggest that it is possible to reverse certain neurodevelopmental disorders in adults. Changes in development, previously thought to be irreparable in adults, were believed to underlie the neurological and psychiatric phenotypes of a range of common mental health problems with a clear developmental component. As a consequence, most researchers have focused their efforts on understanding the molecular and cellular processes that alter development with the hope that early intervention could prevent the emergent pathology. Unexpectedly, several different animal model studies published recently, including animal models of autism, suggest that it may be possible to reverse neurodevelopmental disorders in adults: Addressing the underlying molecular and cellular deficits in adults could in several cases dramatically improve the neurocognitive phenotypes in these animal models. The findings reviewed here provide hope to millions of individuals afflicted with a wide range of neurodevelopmental disorders, including autism, since they suggest that it may be possible to treat or even cure them in adults.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 4%
Netherlands 2 3%
Italy 1 1%
Portugal 1 1%
Poland 1 1%
Unknown 61 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 21 30%
Student > Ph. D. Student 13 19%
Professor 7 10%
Professor > Associate Professor 5 7%
Student > Master 5 7%
Other 13 19%
Unknown 5 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 29 42%
Medicine and Dentistry 11 16%
Neuroscience 9 13%
Psychology 5 7%
Biochemistry, Genetics and Molecular Biology 2 3%
Other 6 9%
Unknown 7 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 August 2020.
All research outputs
#8,733,729
of 16,148,862 outputs
Outputs from Journal of Neurodevelopmental Disorders
#192
of 338 outputs
Outputs of similar age
#111,077
of 252,945 outputs
Outputs of similar age from Journal of Neurodevelopmental Disorders
#9
of 14 outputs
Altmetric has tracked 16,148,862 research outputs across all sources so far. This one is in the 45th percentile – i.e., 45% of other outputs scored the same or lower than it.
So far Altmetric has tracked 338 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 252,945 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.