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| Title |
Exploring mechanisms of excess mortality with early fluid resuscitation: insightsfrom the FEAST trial
|
|---|---|
| Published in |
BMC Medicine, March 2013
|
| DOI | 10.1186/1741-7015-11-68 |
| Pubmed ID | |
| Authors |
Kathryn Maitland, Elizabeth C George, Jennifer A Evans, Sarah Kiguli, Peter Olupot-Olupot, Samuel O Akech, Robert O Opoka, Charles Engoru, Richard Nyeko, George Mtove, Hugh Reyburn, Bernadette Brent, Julius Nteziyaremye, Ayub Mpoya, Natalie Prevatt, Cornelius M Dambisya, Daniel Semakula, Ahmed Ddungu, Vicent Okuuny, Ronald Wokulira, Molline Timbwa, Benedict Otii, Michael Levin, Jane Crawley, Abdel G Babiker, Diana M Gibb, for the FEAST trial group |
| Abstract |
Early rapid fluid resuscitation (boluses) in African children with severe febrile illnesses increases the 48-hour mortality by 3.3% compared with controls (no bolus). We explored the effect of boluses on 48-hour all-cause mortality by clinical presentation at enrolment, hemodynamic changes over the first hour, and on different modes of death, according to terminal clinical events. We hypothesize that boluses may cause excess deaths from neurological or respiratory events relating to fluid overload. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 14 | 26% |
| United States | 8 | 15% |
| Canada | 5 | 9% |
| Australia | 2 | 4% |
| Uruguay | 1 | 2% |
| Poland | 1 | 2% |
| Sweden | 1 | 2% |
| Norway | 1 | 2% |
| France | 1 | 2% |
| Other | 4 | 8% |
| Unknown | 15 | 28% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 34 | 64% |
| Practitioners (doctors, other healthcare professionals) | 11 | 21% |
| Scientists | 6 | 11% |
| Science communicators (journalists, bloggers, editors) | 2 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 322 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 2 | <1% |
| Colombia | 1 | <1% |
| Tanzania, United Republic of | 1 | <1% |
| Vietnam | 1 | <1% |
| Chile | 1 | <1% |
| Israel | 1 | <1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| Denmark | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 311 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 42 | 13% |
| Student > Master | 39 | 12% |
| Researcher | 36 | 11% |
| Student > Bachelor | 36 | 11% |
| Student > Postgraduate | 34 | 11% |
| Other | 85 | 26% |
| Unknown | 50 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 221 | 69% |
| Nursing and Health Professions | 14 | 4% |
| Agricultural and Biological Sciences | 11 | 3% |
| Biochemistry, Genetics and Molecular Biology | 3 | <1% |
| Computer Science | 2 | <1% |
| Other | 11 | 3% |
| Unknown | 60 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 96. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 May 2024.
All research outputs
#475,618
of 26,717,531 outputs
Outputs from BMC Medicine
#353
of 4,298 outputs
Outputs of similar age
#2,998
of 211,927 outputs
Outputs of similar age from BMC Medicine
#8
of 93 outputs
Altmetric has tracked 26,717,531 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,298 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 46.3. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 211,927 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.