Title |
Long-acting methylphenidate formulations in the treatment of attention-deficit/hyperactivity disorder: a systematic review of head-to-head studies
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Published in |
BMC Psychiatry, September 2013
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DOI | 10.1186/1471-244x-13-237 |
Pubmed ID | |
Authors |
David Coghill, Tobias Banaschewski, Alessandro Zuddas, Antonio Pelaz, Antonella Gagliano, Manfred Doepfner |
Abstract |
The stimulant methylphenidate (MPH) has been a mainstay of treatment for attention-deficit/hyperactivity disorder (ADHD) for many years. Owing to the short half-life and the issues associated with multiple daily dosing of immediate-release MPH formulations, a new generation of long-acting MPH formulations has emerged. Direct head-to-head studies of these long-acting MPH formulations are important to facilitate an evaluation of their comparative pharmacokinetics and efficacy; however, to date, relatively few head-to-head studies have been performed.The objective of this systematic review was to compare the evidence available from head-to-head studies of long-acting MPH formulations and provide information that can guide treatment selection. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | <1% |
Colombia | 1 | <1% |
Germany | 1 | <1% |
Chile | 1 | <1% |
Brazil | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 254 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 41 | 16% |
Student > Bachelor | 32 | 12% |
Researcher | 28 | 11% |
Student > Ph. D. Student | 23 | 9% |
Other | 20 | 8% |
Other | 56 | 22% |
Unknown | 60 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 59 | 23% |
Psychology | 45 | 17% |
Pharmacology, Toxicology and Pharmaceutical Science | 16 | 6% |
Social Sciences | 13 | 5% |
Nursing and Health Professions | 10 | 4% |
Other | 49 | 19% |
Unknown | 68 | 26% |