Chronic Liver Disease Produces Accelerated Epigenetic Aging in Other Tissues
Fight Aging!,
Our organs and bodily systems are all interconnected. Organ A relies on organ B in some way for many combinations of A and B…
The Most Affordable Lab-Based Epigenetic Age Tool – The PhenoAge Calculator
Dr.KaraFitzgerald professionals blog,
Biological “clocks” based on epigenetic age have been around for just over a decade. Steve Horvath, a PhD scientist at UCLA…
cfDNA Methylation Analysis Captures the Double Trouble of Inflammaging!
EpiGenie | Epigenetics and Non-Coding RNA News,
Analyzing cell-free (cf)DNA methylation from liquid biopsies represents a non-invasive approach to profile various diseases…
Epigenetics Clocks
Serious Science,
Biologist Vadim Gladyshev on aging, DNA, and the biological age of organs
Associations among NMR-measured inflammatory and metabolic biomarkers and accelerated aging in cardiac catheterization patients
aging-us.net,
The post Associations among NMR-measured inflammatory and metabolic biomarkers and accelerated aging in cardiac catheterization…
Беременность увеличила биологический возраст женщин на два года
N+1: научные статьи, новости, открытия,
Американские и немецкие исследователи подтвердили, что беременность связана с увеличением биологического возраста женщины, которо…
Genome-wide transcriptome profiling and development of age prediction models in the human brain
aging-us.org,
The post Genome-wide transcriptome profiling and development of age prediction models in the human brain appeared first on…
Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions
aging-us.net,
The post Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on…
Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation
aging-us.org,
The post Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions…
Composite dietary antioxidant index associated with delayed biological aging: a population-based study
aging-us.org,
The post Composite dietary antioxidant index associated with delayed biological aging: a population-based study appeared first…
Is Biological Age Testing Accurate or Useful?
Well - New York Times,
New tests promise to tell you if you have the cells of a 30-year-old or a 60-year-old. Here’s what to know about them.
I think I know why methylation clocks are failing
Science Blog,
Methylation clocks promise to revolutionize testing of anti-aging interventions in humans, by measuring their effectiveness in…
New and Notable Studies Using Epigenetic Biological Age Clocks
Dr.KaraFitzgerald professionals blog,
This blog was written by Romilly Hodges MS CNS CDN…
Accelerated Epigenetic Age and Cardiovascular Risk Factors
Fight Aging!,
Epigenetic patterns determine the behavior of a cell, and change constantly in response to cell state and the surrounding…
How do environmental factors impact epigenetic age?
Longevity Technology,
Several environmental factors such as diet, exercise and stress can impact the epigenetic age and can be used to modulate and…
Physical Fitness Correlates with Slower Epigenetic Aging in Newer DNA Methylation Clocks
Fight Aging!,
Epigenetic clocks that measure chronological or biological age are at present largely based on patterns of DNA methylation that…
Aging Is Evolutionary, According to a New Molecular ‘Clock’ That Predicts Age in All Mammals
Science in Seattle,
Gray hair. New wrinkles. Creaky knees. And then there’s the whole, increasing risk of nearly all diseases and the looming…
Scientists Studied 348 Mammals to Discover Why Some Live for Months While Others Last Centuries
Singularity Hub,
Mammals have approximately the same genes. Yet from skittering lab mice to magnificent bowhead whales or the elegant elephant…
Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis
aging-us.org,
The post Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis appeared first on…
Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis
aging-us.net,
The post Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis appeared first on…
Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery
aging-us.net,
The post Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance…
DNAmFitAge: biological age indicator incorporating physical fitness
aging-us.net,
The post DNAmFitAge: biological age indicator incorporating physical fitness appeared first on Aging (Aging-US) Authors.
There is Still Room to Improve Upon Epigenetic Clocks
Fight Aging!,
Researchers here demonstrate that there is still room to improve the accuracy of epigenetic clocks based on patterns of DNA…
Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity
aging-us.net,
The post <a href="https://www.aging-us.com/article/204498/text">Metformin use history and genome-wide DNA methylation profile…
Epigenetic age and lung cancer risk in the CLUE II prospective cohort study
aging-us.org,
The post <a href="https://www.aging-us.com/article/204501/text">Epigenetic age and lung cancer risk in the CLUE II prospective…
Alcohol consumption and epigenetic age acceleration in young adults
aging-us.net,
The post <a href="https://www.aging-us.com/article/204467/text">Alcohol consumption and epigenetic age acceleration in young…
Hallmarks of aging: An expanding universe
Cell,
Aging is a complex and multifactorial process. This reprise of the 2013 “The hallmarks of aging” reviews conceptual progress…
Epigenetic aging is associated with aberrant neural oscillatory dynamics serving visuospatial processing in people with HIV
aging-us.net,
The post <a href="https://www.aging-us.com/article/204437/text">Epigenetic aging is associated with aberrant neural oscillatory…
DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife
aging-us.org,
The post <a href="https://www.aging-us.com/article/204376/text">DNA methylation-based measures of biological aging and…
DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife
aging-us.net,
The post DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal…
Designing a Methylation Clock that Reliably Evaluates Anti-aging Interventions
Science Blog,
Can methylation clocks be relied on in this context? The earliest clocks were trained on biological age only, and yet they…
Centenarians consistently present a younger epigenetic age than their chronological age with four epigenetic clocks based on a small number of CpG sites
aging-us.net,
The post Centenarians consistently present a younger epigenetic age than their chronological age with four epigenetic clocks…
Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older adults
aging-us.net,
The post Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older…
The secret to healthy longevity is happiness, according to new research
Longevity Technology,
Deep Longevity is building a digital model of aging – and its most recent publication shows that mental health is a major…
Epigenetic ‘Clocks’ Predict Animals’ True Biological Age
Feed: All Latest,
A statistical analysis of chemical tags on DNA may help unify disparate theories of aging.
Epigenetic ‘Clocks’ Predict Animals’ True Biological Age
Quanta Magazine,
This time a year ago, Steve Horvath was looking for pangolin DNA. The ancient scaly anteater would be a first for his collection…
DNA’s Molecular Wrinkles: Why You Might Be Older or Younger Than You Think
Science in Seattle,
Age is more than just the number of candles on a birthday cake. In fact, the number of birthdays you’ve had may not be the most…
Correlating Epigenetic Age Acceleration with Survival in Older Individuals
Fight Aging!,
An epigenetic clock produces an epigenetic age from a patient blood or tissue sample. These clocks are trained on data from…
Clozapine Treatment Reduces Epigenetic Age in Male Psychiatric Patients
Fight Aging!,
Researchers are beginning to apply epigenetic clocks to known cases in which drug treatment is associated with a longer life…
Battling Against the Clock: Epigenetic Age Acceleration Impacts COVID-19 Severity
EpiGenie | Epigenetics and Non-Coding RNA News,
Timing is crucial for many aspects of life, and now, a rather timely study demonstrates that the acceleration of our epigenetic…
The science behind the headlines: Turning back the clock on skin cells
Signals Blog,
Image courtesy of…
Can we trust methylation clocks?
Josh Mitteldorf,
A methylation clock is an empirical construct. There is no understanding of physiology or metabolism built into the process.
An evolution of aging
Longevity Technology,
Like everything on this planet, there is history behind the hallmarks of aging; from prokaryotes to humans, we need to go down…
Планы на старость
N+1: научные статьи, новости, открытия,
Кто и как будет искать рецепт омоложения на деньги Юрия Мильнера и Джеффа Безоса
A New Approach to Methylation Clocks
Science Blog,
A new approach to methylation clocks from Morgan Levine uses massive computer resources and sophisticated mathematics. I am…
A New Approach to Methylation Clocks
Josh Mitteldorf,
A new approach to methylation clocks from Morgan Levine uses massive computer resources and sophisticated mathematics. I am…
Exercise and Epigenetics in Neurodegeneration
Fight Aging!,
It is indisputably the case that regular exercise and maintenance of physical fitness into later life lowers the incidence and…
Aging’s ground zero could become rejuvenation clinical target
Longevity Technology,
Unlike what has been suggested since the 19th century, the germ line isn’t ageless and does accumulate damage over time – new…
Studies of Women’s Longevity Offer Clues to Cognitive Resilience for All
Simons Foundation,
The GrimAge Epigenetic Clock Reflects Mortality Risk Differences Between Twins
Fight Aging!,
Epigenetic clocks are correlations identified between physiological age and algorithmic combinations of DNA methylation status…
Breakthrough allows scientists to determine the age of endangered native fish using DNA
CSIRO Blog,
Determining the age of fish has been historically difficult, primarily involving lethal methods. A new DNA test solves this…
Accelerated biological aging seen in prematurely born males
Gizmag Emerging Technology Magazine,
A unique study using epigenetic markers to track biological aging has found prematurely born males, of extremely low birth…
Reducing Measured Epigenetic Age by a Few Years with Diet and Lifestyle Changes
Fight Aging!,
Epigenetic clocks assess changing patterns of DNA methylation at CpG sites on the genome that correlate well with chronological…
New perspective in gerontology: epigenetic rejuvenation
Longevity Technology,
Can biological age be set back by “making the clock tick backwards”? Scientists suggest that a partial phenotypic rejuvenation…
The epigenetics of aging in bats
Nature Ecology & Evolution Community,
With the help of over 20 scientists and a few decades' worth of tissue samples, we have used DNA methylation profiles to…
Higher Cardiovascular Health Score Correlates with Lower Epigenetic Age Acceleration
Fight Aging!,
Epigenetic age acceleration is the degree to which epigenetic age is higher than chronological age. Epigenetic age is assessed…
DNA Methylation Can Take You to Higher Ground!
EpiGenie | Epigenetics and Non-Coding RNA News,
It’s not often that an epigenetics study can elevate you to a higher plane, but uplifting new research into those who live at…
The Epigenetic Clock – From Deep Space to Deep Learning
EpiGenie | Epigenetics and Non-Coding RNA News,
As the year comes to its end, our epigenetic clocks keep on ticking, and hot new DNA methylation-based studies keep rolling in.
GrimAge clock – it’s all a matter of time
Longevity Technology,
Study finds that the DNA methylation GrimAge clock can predict an individual’s lifespan and healthspan with accuracy. It is no…
The Quality of Epigenetic Clocks Continues to Improve
Fight Aging!,
There is at present a diverse exploration of clocks that assess biological age, these clocks constructed as weighted…
GrimAge Outperforms Other Epigenetic Clocks
Fight Aging!,
There are now a variety of epigenetic clocks, weighted combinations of the methylation status of various CpG sites on the…
Proposing an Approach to Obtain Human Data on Combined Interventions and Effects on Aging
Fight Aging!,
With the advent of epigenetic clocks that appear able to measure biological age, researchers are interested in putting these…
Epigenetic reprogramming: the road to reversing time
Longevity Technology,
Epigenetic modifications – also known as “aging clocks” – have emerged as promising markers of aging and accurate predictors of…
Biomarkers for aging – a consensus is needed now more than ever
Longevity Technology,
Slowing, stopping and even reversing aging – how can research progress if we can’t measure success? Biomarkers of aging are…
https://www.livescience.com/four-types-of-aging-revealed.html
Bruce's Blog,
Scientists Discover 4 Distinct Patterns of…
Reviewing the Present Development of Biomarkers of Aging
Fight Aging!,
As this open access paper notes, a great deal of the present work on developing biomarkers of aging involves machine learning.
Biomarkers of aging: AI discovery to therapy
Longevity Technology,
Deep aging clocks – the emergence of Al-based biomarkers of aging and Longevity and their implications in the development of…
https://www.psychologytoday.com/us/blog/the-new-old-age/201910/is-there-biomarker-predicts-your-biological-age
Bruce's Blog,
Is There a Biomarker That Predicts Your Biological Age? After years of study, a test that measures aging is on the horizon.
Pinpointing the molecular mechanisms of ageing
Service news from EMBL-EBI,
Epigenetic clock identifies gene linked to ageing
Epigenetic Age Linked to Allergic Conditions in Children
What is Epigenetics?,
reddit_url = "https://www.whatisepigenetics.com/epigenetic-age-linked-to-allergic-conditions-in-children/"; reddit_title = "Epige…
Progress in Methylation-based Aging Clocks
Josh Mitteldorf,
As I wrote last spring, we can efficiently test treatments for aging once we have an objective measure for the rate of aging. Wi…
Towards a Better Epigenetic Clock
Fight Aging!,
Researchers here report on an improved version of the epigenetic clock. A few carefully defined patterns of DNA methylation…
The Mother of All Clinical Trials, Part II
Josh Mitteldorf,
Part II: Why We Should Trust the Methylation Clocks to Measure…
The Mother of All Clinical Trials, Part II
Science Blog,
Part II: Why We Should Trust the Methylation Clocks to Measure Aging Last week, I proposed that methylation age could be used…
Methylation Aging Clock: An Update
Josh Mitteldorf,
Methylation of DNA is the best-known mode of epigenetic regulation (turning genes on and off). Methylation patterns are stable…
Methylation Aging Clock: An Update
Science Blog,
Methylation of DNA is the best-known mode of epigenetic regulation (turning genes on and off). Methylation patterns are stable…
Activation of Telomerase Will Not Cure Aging
MedicalResearch.com,
MedicalResearch.com Interview with: Douglas P. Kiel, MD, MPH Professor of Medicine Harvard Medical School Director…
What your 'epigenetic clock' tells you about getting older
Forum:Blog,
Epigenetics, the study of how environmental factors and lifestyle choices influence our genes, is helping to shed some extra…
Simple Arterial Health Measures as a Basis for a Biomarker of Aging
Fight Aging!,
As regular readers will know, the development of a robust and cost-effective biomarker of biological age is important. At…
A race against the ageing clock
Service news from EMBL-EBI,
EMBL-EBI researchers release mouse epigenetic clock
DNA Methylation in the Placenta: accelerated aging in pregnancy complications
EpiBeat,
The placenta is a unique organ as it is an extra-embryonic tissue primarily regulated by the fetal genome and shared between…
Does Your Blood Know How You’ll Age?
Pacific Standard. Smart Journalism. Real Solutions.,
A new study suggests patterns in common blood tests could reveal our fates as we get older.Continue reading on Pacific Standard …
Epigenetics and the Direction of Anti-Aging Science
Josh Mitteldorf,
Dear Readers – It’s been a deeply gratifying year for me. Twenty years ago, I first started writing that aging is something…
Epigenetics and the Direction of Anti-Aging Science
Science Blog,
Dear Readers – It’s been a deeply gratifying year for me. Twenty years ago, I first started writing that aging is something…
Biomarkers of aging from epigenetic clocks
On Biology,
We use clocks to keep track of time. When it comes to the term ‘clock’, I think of the hour glass on my dresser, the pendulum…
Stroke Patients Tend to be Biologically Older, as Measured by DNA Methylation
Fight Aging!,
Today I thought I'd point out one of the recent results to emerge from the discovery that DNA methylation patterns correlate…
DNA methylation and hydroxymethylation in the aging brain – Not less, but where
EpiBeat,
Changes in DNA methylation have long been an area of interest for neurobiology of aging researchers. With the recent reports…
CRISPR update
Josh Mitteldorf,
I believe that all we have to do to make ourselves younger is to turn on the genes that were expressed when we were young, and…
Epigenetics of Aging, and Prospects for Rejuvenation
Josh Mitteldorf,
Last week, I attended the tail end of a Keystone conference on Epigenetic Regulation of Aging, followed by a one-day…
Cellular clock may help improve cancer treatment, forensic science
Genetic Literacy Project,
Scientists have found that your cells keeps track of aging. This clock may have important implications for how we treat cancer…
One Week, Two Innovations in Aging and Health
Josh Mitteldorf,
Incremental advances in understanding the genetics, epigenetics, and biochemistry of aging are gradually pushing the field…
High-profile aging paper posts old erratum, requested by author more than one year prior
Retraction Watch,
Genome Biology has partially retracted a high-profile paper about an epigenetic biomarker of aging – a year and a half after…
Life, death, and DNA methylation
The Molecular Ecologist,
“My biological clock is TICKING LIKE THIS!” – My Cousin…
Quick Notes from Quebec
Josh Mitteldorf,
(or “Short Takes from Sherbrooke”), Center for Research on Aging, Symposium Nov 2-4 “Why does the cell appear to be shooting…
Methylating much?
BioMed Central blog,
Our readers might have gotten distracted this month by discussions on whether it is right or wrong for Illumina to limit…
2013 in Genome Biology… according to F1000 reviewers
BioMed Central blog,
In 2013, BioMed Central's blog and Biome magazine have dedicated quite some space to considering alternative models of peer…
Three links in Aging, Regenerative Medicine
Pimm - Partial immortalization,
1. DNA methylation age of human tissues and cell types by Steve Horvath: This is the type of relevant data mining study most…
Epigenetic Clock Marks Age of Human Tissues and Cells
NIH Research Matters,
The age of many human tissues and cells is reflected in chemical changes to DNA. The finding provides insights for cancer, aging…
Young at Heart, Literally – Body Parts Age at Different Rates
Discover Top Stories,
Move over, anti-aging cream. Researchers have found a new biological clock in human DNA that determines the rate at which…