Title |
Incidence, characteristics and risk factors of adverse drug reactions in hospitalized children – a prospective observational cohort study of 6,601 admissions
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Published in |
BMC Medicine, November 2013
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DOI | 10.1186/1741-7015-11-237 |
Pubmed ID | |
Authors |
Signe Thiesen, Elizabeth J Conroy, Jennifer R Bellis, Louise E Bracken, Helena L Mannix, Kim A Bird, Jennifer C Duncan, Lynne Cresswell, Jamie J Kirkham, Matthew Peak, Paula R Williamson, Anthony J Nunn, Mark A Turner, Munir Pirmohamed, Rosalind L Smyth |
Abstract |
Adverse drug reactions (ADRs) are an important cause of harm in children. Current data are incomplete due to methodological differences between studies: only half of all studies provide drug data, incidence rates vary (0.6% to 16.8%) and very few studies provide data on causality, severity and risk factors of pediatric ADRs. We aimed to determine the incidence of ADRs in hospitalized children, to characterize these ADRs in terms of type, drug etiology, causality and severity and to identify risk factors. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 5 | 31% |
United Kingdom | 2 | 13% |
Ireland | 1 | 6% |
Canada | 1 | 6% |
El Salvador | 1 | 6% |
Unknown | 6 | 38% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 12 | 75% |
Scientists | 2 | 13% |
Science communicators (journalists, bloggers, editors) | 1 | 6% |
Practitioners (doctors, other healthcare professionals) | 1 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Korea, Republic of | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 107 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 12 | 11% |
Researcher | 9 | 8% |
Student > Postgraduate | 9 | 8% |
Student > Doctoral Student | 9 | 8% |
Student > Ph. D. Student | 8 | 7% |
Other | 26 | 24% |
Unknown | 36 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 39 | 36% |
Pharmacology, Toxicology and Pharmaceutical Science | 13 | 12% |
Nursing and Health Professions | 7 | 6% |
Agricultural and Biological Sciences | 3 | 3% |
Chemistry | 2 | 2% |
Other | 8 | 7% |
Unknown | 37 | 34% |