↓ Skip to main content

Salivary epidermal growth factor correlates with hospitalization length in rotavirus infection

Overview of attention for article published in BMC Infectious Diseases, May 2017
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

twitter
7 tweeters

Readers on

mendeley
8 Mendeley
Title
Salivary epidermal growth factor correlates with hospitalization length in rotavirus infection
Published in
BMC Infectious Diseases, May 2017
DOI 10.1186/s12879-017-2463-0
Pubmed ID
Authors

J. Gómez-Rial, M. J. Curras-Tuala, C. Talavero-González, C. Rodríguez-Tenreiro, L. Vilanova-Trillo, A. Gómez-Carballa, I. Rivero-Calle, A. Justicia-Grande, J. Pardo-Seco, L. Redondo-Collazo, A. Salas, F. Martinón-Torres

Abstract

The IFI27 interferon gene expression has been found to be largely increased in rotavirus (RV)-infected patients. IFI27 gene encodes for a protein of unknown function, very recently linked to epidermal proliferation and related to the epidermal growth factor (EGF) protein. The EGF is a low-molecular-weight polypeptide that is mainly produced by submandibular and parotid glands, and it plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. Our aim was to determine salivary EGF levels in RV-infected patients in order to establish its potential relationship with IFI27 increased expression and EGF-mediated mucosal protection in RV infection. We conducted a prospective comparative study using saliva samples from 27 infants infected with RV (sampled at recruitment during hospital admission and at convalescence, i.e. at least 3 months after recovery) and from 36 healthy control children. Median (SD) EGF salivary concentration was 777 (529) pg/ml in RV-infected group at acute phase and 356 (242) pg/m at convalescence, while it was 337 (119) pg/ml in the healthy control group. A significant association was found between EGF levels and hospitalization length of stay (P-value = 0.022; r(2) = -0.63). The salivary levels of EGF are significantly increased during the acute phase of natural RV infection, and relate to length of hospitalization. Further assessment of this non-invasive biomarker in RV disease is warranted.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 2 25%
Student > Ph. D. Student 2 25%
Student > Postgraduate 1 13%
Researcher 1 13%
Librarian 1 13%
Other 1 13%
Readers by discipline Count As %
Medicine and Dentistry 3 38%
Biochemistry, Genetics and Molecular Biology 2 25%
Unspecified 2 25%
Agricultural and Biological Sciences 1 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 June 2017.
All research outputs
#2,715,383
of 11,342,318 outputs
Outputs from BMC Infectious Diseases
#851
of 4,216 outputs
Outputs of similar age
#78,375
of 267,055 outputs
Outputs of similar age from BMC Infectious Diseases
#26
of 117 outputs
Altmetric has tracked 11,342,318 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,216 research outputs from this source. They receive a mean Attention Score of 4.2. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,055 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 117 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.