| Title |
Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report
|
|---|---|
| Published in |
Nutrition & Metabolism, April 2010
|
| DOI | 10.1186/1743-7075-7-33 |
| Pubmed ID | |
| Authors |
Giulio Zuccoli, Norina Marcello, Anna Pisanello, Franco Servadei, Salvatore Vaccaro, Purna Mukherjee, Thomas N Seyfried |
| Abstract |
Management of glioblastoma multiforme (GBM) has been difficult using standard therapy (radiation with temozolomide chemotherapy). The ketogenic diet is used commonly to treat refractory epilepsy in children and, when administered in restricted amounts, can also target energy metabolism in brain tumors. We report the case of a 65-year-old woman who presented with progressive memory loss, chronic headaches, nausea, and a right hemisphere multi-centric tumor seen with magnetic resonance imaging (MRI). Following incomplete surgical resection, the patient was diagnosed with glioblastoma multiforme expressing hypermethylation of the MGMT gene promoter. |
X Demographics
The data shown below were collected from the profiles of 35 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 26% |
| United Kingdom | 2 | 6% |
| Spain | 2 | 6% |
| South Africa | 1 | 3% |
| Ireland | 1 | 3% |
| Japan | 1 | 3% |
| Canada | 1 | 3% |
| Unknown | 18 | 51% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 22 | 63% |
| Practitioners (doctors, other healthcare professionals) | 9 | 26% |
| Scientists | 4 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 366 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 1% |
| Israel | 1 | <1% |
| Canada | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 359 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 86 | 23% |
| Student > Bachelor | 57 | 16% |
| Student > Ph. D. Student | 37 | 10% |
| Researcher | 36 | 10% |
| Student > Postgraduate | 19 | 5% |
| Other | 57 | 16% |
| Unknown | 74 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 105 | 29% |
| Agricultural and Biological Sciences | 46 | 13% |
| Nursing and Health Professions | 40 | 11% |
| Biochemistry, Genetics and Molecular Biology | 28 | 8% |
| Neuroscience | 19 | 5% |
| Other | 43 | 12% |
| Unknown | 85 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 117. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 February 2024.
All research outputs
#361,267
of 25,582,611 outputs
Outputs from Nutrition & Metabolism
#63
of 1,019 outputs
Outputs of similar age
#919
of 104,132 outputs
Outputs of similar age from Nutrition & Metabolism
#3
of 12 outputs
Altmetric has tracked 25,582,611 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,019 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 28.8. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,132 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.