Report for: Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report

Title	Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report
Published in	Nutrition & Metabolism, January 2010
DOI	10.1186/1743-7075-7-33
Pubmed ID	20412570
Authors	Giulio Zuccoli, Norina Marcello, Anna Pisanello, Franco Servadei, Salvatore Vaccaro, Purna Mukherjee, Thomas N Seyfried
Abstract	Management of glioblastoma multiforme (GBM) has been difficult using standard therapy (radiation with temozolomide chemotherapy). The ketogenic diet is used commonly to treat refractory epilepsy in children and, when administered in restricted amounts, can also target energy metabolism in brain tumors. We report the case of a 65-year-old woman who presented with progressive memory loss, chronic headaches, nausea, and a right hemisphere multi-centric tumor seen with magnetic resonance imaging (MRI). Following incomplete surgical resection, the patient was diagnosed with glioblastoma multiforme expressing hypermethylation of the MGMT gene promoter.

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Twitter Demographics

The data shown below were collected from the profiles of 31 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Geographical breakdown

Country	Count	As %
United States	10	32%
United Kingdom	2	6%
Spain	2	6%
Canada	1	3%
Ireland	1	3%
South Africa	1	3%
Japan	1	3%
Libya	1	3%
Unknown	12	39%

Demographic breakdown

Type	Count	As %
Members of the public	20	65%
Practitioners (doctors, other healthcare professionals)	9	29%
Scientists	2	6%

Mendeley readers

The data shown below were compiled from readership statistics for 293 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country	Count	As %
United States	4	1%
Canada	1	<1%
Israel	1	<1%
Belgium	1	<1%
Brazil	1	<1%
Unknown	285	97%

Demographic breakdown

Readers by professional status	Count	As %
Student > Master	83	28%
Student > Bachelor	52	18%
Student > Ph. D. Student	34	12%
Researcher	31	11%
Student > Postgraduate	18	6%
Other	44	15%
Unknown	31	11%

Readers by discipline	Count	As %
Medicine and Dentistry	96	33%
Agricultural and Biological Sciences	45	15%
Nursing and Health Professions	35	12%
Biochemistry, Genetics and Molecular Biology	25	9%
Neuroscience	17	6%
Other	35	12%
Unknown	40	14%

Attention Score in Context

This research output has an Altmetric Attention Score of 108. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 November 2020.

All research outputs

#210,477

of 16,580,141 outputs

Outputs from Nutrition & Metabolism

#34

of 802 outputs

Outputs of similar age

#794

of 95,325 outputs

Outputs of similar age from Nutrition & Metabolism

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So far Altmetric has tracked 802 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.3. This one has done particularly well, scoring higher than 95% of its peers.

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Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report

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