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Dosage compensation is less effective in birds than in mammals

Overview of attention for article published in BMC Biology, March 2007
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Title
Dosage compensation is less effective in birds than in mammals
Published in
BMC Biology, March 2007
DOI 10.1186/jbiol53
Pubmed ID
Authors

Yuichiro Itoh, Esther Melamed, Xia Yang, Kathy Kampf, Susanna Wang, Nadir Yehya, Atila Van Nas, Kirstin Replogle, Mark R Band, David F Clayton, Eric E Schadt, Aldons J Lusis, Arthur P Arnold

Abstract

In animals with heteromorphic sex chromosomes, dosage compensation of sex-chromosome genes is thought to be critical for species survival. Diverse molecular mechanisms have evolved to effectively balance the expressed dose of X-linked genes between XX and XY animals, and to balance expression of X and autosomal genes. Dosage compensation is not understood in birds, in which females (ZW) and males (ZZ) differ in the number of Z chromosomes.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 159 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 3%
United Kingdom 2 1%
Czechia 1 <1%
Switzerland 1 <1%
Argentina 1 <1%
Ireland 1 <1%
Unknown 149 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 45 28%
Student > Bachelor 26 16%
Researcher 25 16%
Student > Master 14 9%
Professor > Associate Professor 10 6%
Other 25 16%
Unknown 14 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 86 54%
Biochemistry, Genetics and Molecular Biology 37 23%
Neuroscience 6 4%
Environmental Science 3 2%
Medicine and Dentistry 3 2%
Other 6 4%
Unknown 18 11%