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Ki67 expression and the effect of neo-adjuvant chemotherapy on luminal HER2-negative breast cancer

Overview of attention for article published in BMC Cancer, July 2014
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Title
Ki67 expression and the effect of neo-adjuvant chemotherapy on luminal HER2-negative breast cancer
Published in
BMC Cancer, July 2014
DOI 10.1186/1471-2407-14-550
Pubmed ID
Authors

Yoshiya Horimoto, Atsushi Arakawa, Masahiko Tanabe, Hiroshi Sonoue, Fumie Igari, Koji Senuma, Emi Tokuda, Hideo Shimizu, Taijiro Kosaka, Mitsue Saito

Abstract

Patients with luminal HER2-negative tumours have a favourable prognosis. However, there is a subpopulation in which poorer outcomes are obtained with endocrine therapy alone. This subpopulation is considered to benefit from chemotherapy. However, the significance of chemotherapy for those with luminal tumours has decreased due to recent changes in treatment strategies. Thus, it is often difficult to determine whether we should recommend chemotherapy to such patients in clinical practice. We investigated Ki67 expression, as a means of predicting the responses of luminal HER2-negative breast cancer patients to neo-adjuvant chemotherapy (NAC), in order to identify a subpopulation that would benefit from these treatments.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 13%
Unknown 7 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 38%
Student > Master 2 25%
Student > Postgraduate 1 13%
Student > Ph. D. Student 1 13%
Student > Bachelor 1 13%
Other 0 0%
Readers by discipline Count As %
Medicine and Dentistry 5 63%
Nursing and Health Professions 1 13%
Agricultural and Biological Sciences 1 13%
Unspecified 1 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2014.
All research outputs
#6,283,865
of 8,282,457 outputs
Outputs from BMC Cancer
#2,237
of 3,485 outputs
Outputs of similar age
#117,153
of 180,057 outputs
Outputs of similar age from BMC Cancer
#93
of 142 outputs
Altmetric has tracked 8,282,457 research outputs across all sources so far. This one is in the 13th percentile – i.e., 13% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,485 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
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We're also able to compare this research output to 142 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.