Title |
Immunomodulatory activity of Dioscorea membranacea Pierre rhizomes and of its main active constituent Dioscorealide B
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Published in |
BMC Complementary Medicine and Therapies, October 2014
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DOI | 10.1186/1472-6882-14-403 |
Pubmed ID | |
Authors |
Sumalee Panthong, Srisopa Ruangnoo, Pakakrong Thongdeeying, Busarawan Sriwanthana, Arunporn Itharat |
Abstract |
The rhizomes of Dioscorea membranacea Pierre, also called Hua-Khao-Yen by Thai name, are used as ingredients in many Thai traditional medicines for the alternative or complementary treatment of cancer and AIDs. Preliminary in vitro studies have indicated that D. membranacea extracts exhibited high cytotoxic activity with several cancer cell lines, but the underlining mechanisms are far from clear. The aims of this study were to investigate the effects of ethanolic and aqueous crude extracts from D. membranacea Pierre, and pure compound from D. membranacea Pierre, Dioscorealide B, on natural killer cells activity and on lymphocyte proliferation. |
X Demographics
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United States | 1 | 25% |
United Kingdom | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 4 | 29% |
Other | 1 | 7% |
Lecturer | 1 | 7% |
Student > Doctoral Student | 1 | 7% |
Researcher | 1 | 7% |
Other | 2 | 14% |
Unknown | 4 | 29% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 3 | 21% |
Biochemistry, Genetics and Molecular Biology | 2 | 14% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 14% |
Unknown | 7 | 50% |