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Astragalus saponins modulates colon cancer development by regulating calpain-mediated glucose-regulated protein expression

Overview of attention for article published in BMC Complementary Medicine and Therapies, October 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
3 news outlets

Citations

dimensions_citation
25 Dimensions

Readers on

mendeley
37 Mendeley
Title
Astragalus saponins modulates colon cancer development by regulating calpain-mediated glucose-regulated protein expression
Published in
BMC Complementary Medicine and Therapies, October 2014
DOI 10.1186/1472-6882-14-401
Pubmed ID
Authors

Yue Wang, Kathy K Auyeung, Xiaoyu Zhang, Joshua K Ko

Abstract

Glucose-regulated proteins (GRP) are induced in the cancer microenvironment to promote tumor survival, metastasis and drug resistance. AST was obtained from the medicinal plant Astragalus membranaceus, which possesses anti-tumor and pro-apoptotic properties in colon cancer cells and tumor xenograft. The present study aimed to investigate the involvement of GRP in endoplasmic reticulum (ER) stress-mediated apoptosis during colon cancer development, with focus on the correlation between AST-evoked regulation of GRP and calpain activation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 3%
Unknown 36 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 14%
Student > Master 5 14%
Student > Bachelor 5 14%
Student > Doctoral Student 2 5%
Lecturer 2 5%
Other 7 19%
Unknown 11 30%
Readers by discipline Count As %
Medicine and Dentistry 10 27%
Agricultural and Biological Sciences 5 14%
Biochemistry, Genetics and Molecular Biology 3 8%
Business, Management and Accounting 2 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 6 16%
Unknown 9 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2023.
All research outputs
#1,494,656
of 23,565,002 outputs
Outputs from BMC Complementary Medicine and Therapies
#244
of 3,708 outputs
Outputs of similar age
#17,656
of 257,469 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#4
of 106 outputs
Altmetric has tracked 23,565,002 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,708 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 257,469 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.