RT @ajhatswell: @statsepi Not directly directly but very relevant, is this excellent paper that you can cite. The problem with using histo…
RT @ajhatswell: @graham74GC Fantastic paper by Moroz et al. looking at when historical data was used to power trials, unsurprisingly in sai…
Comparison group participants often do better than expected in sample size calculation, 3.8% better on average http://t.co/OlCZLXZ6VZ
Comparison group participants often do better than expected in sample size calculation, 3.8% better on average http://t.co/OlCZLXZ6VZ
Comparison group participants often do better than expected in sample size calculation, 3.8% better on average http://t.co/OlCZLXZ6VZ
Comparison group participants often do better than expected in sample size calculation, 3.8% better on average http://t.co/OlCZLXZ6VZ
Comparison group participants often do better than expected in sample size calculation, 3.8% better on average http://t.co/OlCZLXZ6VZ
Comparison group participants often do better than expected in sample size calculation, 3.8% better on average http://t.co/OlCZLXZ6VZ
Vital @WorldSIOP @MedicalEvidence Historically controlled studies likely to overestimate benefit of new Rx inPaed Onc http://t.co/XCkpgLl3Rm
Anticipated & actual control group #outcomes in #RCTs in ped oncol: evidence of bias in historically control studies; http://t.co/LJucNNQfM8
Vital @WorldSIOP @MedicalEvidence Historically controlled studies likely to overestimate benefit of new Rx inPaed Onc http://t.co/XCkpgLl3Rm
Historically controlled studies likely to overestimate the benefit of new treatments in pediatric oncology, #Trials: http://t.co/xeRaY43y6o
Historically controlled studies likely to overestimate the benefit of new treatments in pediatric oncology, #Trials: http://t.co/xeRaY43y6o
Historically controlled pediatric #oncology studies are biased in favor of novel treatment, new research in #Trials: http://t.co/Iecnu46ril