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Host-virus interaction: a new role for microRNAs

Overview of attention for article published in Retrovirology, October 2006
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)

Mentioned by

2 patents
2 Wikipedia pages


177 Dimensions

Readers on

219 Mendeley
3 CiteULike
2 Connotea
Host-virus interaction: a new role for microRNAs
Published in
Retrovirology, October 2006
DOI 10.1186/1742-4690-3-68
Pubmed ID

Vinod Scaria, Manoj Hariharan, Souvik Maiti, Beena Pillai, Samir K Brahmachari


MicroRNAs (miRNAs) are a new class of 18-23 nucleotide long non-coding RNAs that play critical roles in a wide spectrum of biological processes. Recent reports also throw light into the role of microRNAs as critical effectors in the intricate host-pathogen interaction networks. Evidence suggests that both virus and hosts encode microRNAs. The exclusive dependence of viruses on the host cellular machinery for their propagation and survival also make them highly susceptible to the vagaries of the cellular environment like small RNA mediated interference. It also gives the virus an opportunity to fight and/or modulate the host to suite its needs. Thus the range of interactions possible through miRNA-mRNA cross-talk at the host-pathogen interface is large. These interactions can be further fine-tuned in the host by changes in gene expression, mutations and polymorphisms. In the pathogen, the high rate of mutations adds to the complexity of the interaction network. Though evidence regarding microRNA mediated cross-talk in viral infections is just emerging, it offers an immense opportunity not only to understand the intricacies of host-pathogen interactions, and possible explanations to viral tropism, latency and oncogenesis, but also to develop novel biomarkers and therapeutics.

Mendeley readers

The data shown below were compiled from readership statistics for 219 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 2%
India 3 1%
Germany 1 <1%
Ethiopia 1 <1%
Chile 1 <1%
Ireland 1 <1%
Colombia 1 <1%
Portugal 1 <1%
New Zealand 1 <1%
Other 6 3%
Unknown 198 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 64 29%
Researcher 50 23%
Student > Master 16 7%
Student > Bachelor 14 6%
Student > Doctoral Student 13 6%
Other 44 20%
Unknown 18 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 119 54%
Biochemistry, Genetics and Molecular Biology 36 16%
Medicine and Dentistry 13 6%
Immunology and Microbiology 10 5%
Veterinary Science and Veterinary Medicine 3 1%
Other 12 5%
Unknown 26 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 December 2021.
All research outputs
of 22,590,459 outputs
Outputs from Retrovirology
of 1,100 outputs
Outputs of similar age
of 65,680 outputs
Outputs of similar age from Retrovirology
of 1 outputs
Altmetric has tracked 22,590,459 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,100 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 65,680 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them