RT @cremieuxrecueil: there will be few theory-building enterprises and many discoveries will be foregone, for no other reason than dislikin…
there will be few theory-building enterprises and many discoveries will be foregone, for no other reason than disliking effects that feel small. Effect size source: https://t.co/SREFAyC84x Conversion: https://t.co/XaO1pNBBla Chance to r: https://t.co/VN
@SpecialSitsNews Funny headline Imagine if read: 85 percent of people who take GLP-1 drugs lose weight despite genetics Btw A study on average drug efficacy https://t.co/dHzQ3PUNLl
@DBDouble @votesforoysters @CapitalistFraud For sure, but the size effect of metilphenidate for ADHD is above other neuro- & psycho- medications. So you have a better case going against meds for hypertension, antidepressants or statins. https://t.co/N
I wasn't able to maintain it forever but for 40 trials I achieved mean=2.9 and p=0.00965 and effect size (SDM) = 0.37 that's about as effective as antidepressants and significantly higher than aspirin. https://t.co/We1GZZbIUE Within the "medium effect" siz
@DeDurkheim @SEthanMilne I feel like I remember something like this but now I can't recall exactly! What does come to mind is this one about common medicines, which might be useful for the same purposes: https://t.co/zmkd6w5UUE
Para profundizar: Sobre valores teóricos de terapias: https://t.co/TO6KM6cK1V Sobre otras medicaciones: https://t.co/YeELpRV4ZC
@waughsminx @ElonMuskAOC @stclairashley It's overrated in general: https://t.co/DkkjcooR18
@stxpdx @stclairashley Correct: https://t.co/DkkjcooR18
@TheRabbitHole84 @stclairashley Therapy is a waste of money: https://t.co/DkkjcooR18
@JDW303i @stclairashley The effect size of psychotherapy and psychopharmacology is on the low end of common medications. Psychotherapy is no better than self-help either. No one should need to go to therapy: https://t.co/FYnfbMgRiL https://t.co/L6scnW6sVv
Summary of effect sizes for common pharmacological treatments https://t.co/tUXPaIjX2R https://t.co/aw0qLExnt1
@Neale_Print @axios Healthcare shouldn't be a business where companies whose entire purpose is to profit exist. Meds aren't "proven" to be effective. You can't "prove" anything. The "better than placebo" standard is partly why we have such poor treatment
RT @NaudetFlorian: Some try to reduce this complexity with a simple analogy. Small effect sizes of antidepressants are in the same range of…
RT @NaudetFlorian: Some try to reduce this complexity with a simple analogy. Small effect sizes of antidepressants are in the same range of…
Some try to reduce this complexity with a simple analogy. Small effect sizes of antidepressants are in the same range of effect sizes as all other medical therapeutics... -> Therefore there is no problem. https://t.co/w6v1pEtNXl
@DrZoffness has been saying this too.
RT @dr_ilardi: Antidepressants are not terribly effective for treating depression (on average). The chart below compares their clinical im…
Antidepressants are not terribly effective for treating depression (on average). The chart below compares their clinical impact with that of other commonly prescribed med classes (all vs placebo control), and shows how poorly they tend to fare. 1/3 http
@stevemagness Most widely used meds are far more effective than antidepressants (see below). And this 2015 SMD estimate for antidepressants (0.38) is actually higher than in more recent metas (0.30) that include all the unpublished “file drawer”’studies:
一般的な医薬品はどの程度有効か:主要医薬品のメタアナリシスに基づく視点 https://t.co/c94h12Dh3m 一般的に使用されている薬物17種類中11種類しか(有効性を表すのによく用いられる統計的指標において)臨床的に重要な差を示さず、比較的効果の小さい薬物療法があることがわかった。
@arthur_alb1 @mab_sp125 @LuisCLCorreia Então, o que eu discordo é que o tipo de desfecho escolhido pode gerar tamanhos de efeito maiores. https://t.co/VN4Cnq4tTX
*Their drugs*: Ask your doctor if NearlyKillYouAtrol w/ 100 + side effects, is right for you." *As soon as you start using alternative medicine* Them: THAT'S ALL PLACEBO! (meanwhile their drugs are hardly better than a placebo https://t.co/W2n4TNPeUd)
@dchristmas @peterkinderman When it comes to the effect sizes of commonly used drugs, antidepressants are among the worst.... 👇 Also, what's relevant is whether the drug you prescribe has clinically meaningful effects (not what its relative effect size is
@sunlorrie Courts WILL decide that. What each vaxxer needs to decide is whether refusing to take a drug is basic human right. Canadians so used to being fed useless and often harmful drugs by inefficient “free” OHIP, find this shocking. https://t.co/AAWxWb
一般的な薬の効果:主要な薬のメタアナリシスに基づく展望 https://t.co/C14WDenVj1
RT @syuichiao89: 一般的な薬理学的治療の効果量の要約 https://t.co/DMwV5lKnCK https://t.co/fDcFNxCVOw
RT @syuichiao89: 一般的な薬理学的治療の効果量の要約 https://t.co/DMwV5lKnCK https://t.co/fDcFNxCVOw
一般的な薬理学的治療の効果量の要約 https://t.co/DMwV5lKnCK https://t.co/fDcFNxCVOw
RT @eturnermd1: "Drs may believe that all patients respond to drugs & none to placebo, but neither statement is true bc there is no ideal d…
@SonjaCowling @fredemag See this article of comparisons of effectiveness
Here’s a comparison between psych treatments and those in the rest of medicine btw Do better and don’t publish such mince again
RT @susan_bewley: Fabulous perspective with diagrams showing relative effectiveness (and not) across major drugs @HealthWatchUK
RT @susan_bewley: Fabulous perspective with diagrams showing relative effectiveness (and not) across major drugs @HealthWatchUK
RT @susan_bewley: Fabulous perspective with diagrams showing relative effectiveness (and not) across major drugs @HealthWatchUK
Fabulous perspective with diagrams showing relative effectiveness (and not) across major drugs @HealthWatchUK
RT @pash22: How effective are common medications: a perspective based on meta-analyses of major drugs https://t.co/uOYbi4l7WR via @StefanLe…
A great article and exposes the confirmation bias amongst us physicians when patients get better and we attribute it to the drug rather than spontaneous healing.
How effective are common medications: a perspective based on meta-analyses of major drugs https://t.co/uOYbi4l7WR via @StefanLeucht et al @TomPMarshall @susan_bewley
RT @JRBneuropsiq: How effective are common medications: a perspective based on meta-analyses of major drugs @SameiHuda https://t.co/yEfhzqA…
RT @JRBneuropsiq: How effective are common medications: a perspective based on meta-analyses of major drugs @SameiHuda https://t.co/yEfhzqA…
RT @eturnermd1: "Drs may believe that all patients respond to drugs & none to placebo, but neither statement is true bc there is no ideal d…
Et tu, ACE-inhibitors 😣🗡
RT @JRBneuropsiq: How effective are common medications: a perspective based on meta-analyses of major drugs @SameiHuda https://t.co/yEfhzqA…
RT @eturnermd1: "Drs may believe that all patients respond to drugs & none to placebo, but neither statement is true bc there is no ideal d…
"Drs may believe that all patients respond to drugs & none to placebo, but neither statement is true bc there is no ideal drug & many disorders remit spontaneously...Our preference for black or white over shades of grey is convenient but it can off
@ITattum @HoratioClare @Thomas_D_Lee Here’s a link to a paper comparing psychiatric with general medical treatments
RT @JRBneuropsiq: How effective are common medications: a perspective based on meta-analyses of major drugs @SameiHuda https://t.co/yEfhzqA…
RT @JRBneuropsiq: How effective are common medications: a perspective based on meta-analyses of major drugs @SameiHuda https://t.co/yEfhzqA…
Y, además, buenos consejos: "In general, relative risk reductions suggest larger differences than absolute risk difference." Mejor buscar y reportar las diferencias absolutas de riesgo (o las dos). Menos dramática, eso sí.
RT @JRBneuropsiq: How effective are common medications: a perspective based on meta-analyses of major drugs @SameiHuda https://t.co/yEfhzqA…
RT @carlos_arnaud: Que bueno artículo La eficacia de los medicamentos en las principales enfermedades Médicas Vemos que los antidepresivos…
Que bueno artículo La eficacia de los medicamentos en las principales enfermedades Médicas Vemos que los antidepresivos son tienen un mayor tamaño del efecto que las estatinas por ejemplo Me hubiera gustado ver al final los NNT
RT @JRBneuropsiq: How effective are common medications: a perspective based on meta-analyses of major drugs @SameiHuda https://t.co/yEfhzqA…
RT @JRBneuropsiq: How effective are common medications: a perspective based on meta-analyses of major drugs @SameiHuda https://t.co/yEfhzqA…
How effective are common medications: a perspective based on meta-analyses of major drugs @SameiHuda https://t.co/yEfhzqAFCb
RT @JRBneuropsiq: @ISEPPDirector @VegaPortales @awaisaftab Putting things in perspective: According to this review psychopharmacologic tre…
RT @JRBneuropsiq: @ISEPPDirector @VegaPortales @awaisaftab Putting things in perspective: According to this review psychopharmacologic tre…
RT @JRBneuropsiq: @ISEPPDirector @VegaPortales @awaisaftab Putting things in perspective: According to this review psychopharmacologic tre…
RT @JRBneuropsiq: @ISEPPDirector @VegaPortales @awaisaftab Putting things in perspective: According to this review psychopharmacologic tre…
RT @JRBneuropsiq: @ISEPPDirector @VegaPortales @awaisaftab Putting things in perspective: According to this review psychopharmacologic tre…
@ISEPPDirector @VegaPortales @awaisaftab Putting things in perspective: According to this review psychopharmacologic treatments are in the middle range of efficacy compared to other medical treatments. However, we should be realistic & care for psycho
@medicblasto Y si miramos la efectividad de algunos medicamentos, mira por donde andan en la escala de d de Cohen. https://t.co/UUCnzqkSET
@doctorveera Thanks! What do you mean by a large effect? they mention that "The 123 loci explained 1.1% of the variance in daytime napping", so effects are very small. The drug effect is prob much larger, do we know how to explain this gap? Examples of med
RT @FBpsy: ¿Y en otras ciencias? Por comparar con algo que conozcamos todas/os, los meta-análisis indican que muchas medicinas de uso popul…
¿Y en otras ciencias? Por comparar con algo que conozcamos todas/os, los meta-análisis indican que muchas medicinas de uso popular tienen rango de efectos de tamaño similar (mediano). https://t.co/P0M5tt9MLY https://t.co/pds99PZTDH
@ed_hagen for similarity of effect sizes of psychiatric medications and non-psychiatric ones see https://t.co/Hwe207Q8yD or https://t.co/n5NuAVpc3U this is not to say you have to be wrong but if common medications we feel effective from daily use have sim
@spencerdrake64 @MommyLiberty @RedWhiteandBlo5 @GitRDoneLarry No, it's more terrifying than that. If a drug is works 45% and the placebo works 30%, due to "math" they can legally claim it has a 50% efficacy rate. But Mater blocked me, so to respect his w
"We found that some of the medications have relatively low effect sizes with only 11 of 17...showing a minimal clinically important difference. Efficacy was often established based on surrogate outcomes + not the more relevant patient-oriented outcomes."
What is an educationally important difference? This paper argues half-a-standard deviation for a clinically important difference in medicine and reviews the evidence on some common treatments. https://t.co/FZYq8RxWW5 https://t.co/VtHGmmX7m1
RT @EstebanDL: Artículo de opinión sobre la dimensión real de algunas intervenciones farmacológicas Incluidas estatinas https://t.co/Eo8ypC…
Artículo de opinión sobre la dimensión real de algunas intervenciones farmacológicas Incluidas estatinas https://t.co/Eo8ypCtvpg https://t.co/uWkbtBy0ZQ
RT @PabloRichly: Esta comparación de la eficacia de algunos de los medicamentos más frecuentemente utilizados permite tomar perspectiva de…
Esta comparación de la eficacia de algunos de los medicamentos más frecuentemente utilizados permite tomar perspectiva de la de los psicofármacos. https://t.co/4a8sfA5ENK
RT @Martin_Ploederl: Antidepressants vs. other pharmacological treatments. Note that the effect size for AD is in fact smaller than depic…
RT @Martin_Ploederl: Antidepressants vs. other pharmacological treatments. Note that the effect size for AD is in fact smaller than depic…
RT @Martin_Ploederl: Antidepressants vs. other pharmacological treatments. Note that the effect size for AD is in fact smaller than depic…
RT @pash22: Summary of effect sizes for common pharmacological treatments https://t.co/drslmnqNfj https://t.co/68oQMzjzRr
RT @Martin_Ploederl: Antidepressants vs. other pharmacological treatments. Note that the effect size for AD is in fact smaller than depic…
RT @pash22: Summary of effect sizes for common pharmacological treatments https://t.co/drslmnqNfj https://t.co/68oQMzjzRr
RT @Martin_Ploederl: Antidepressants vs. other pharmacological treatments. Note that the effect size for AD is in fact smaller than depic…
RT @pash22: @HengartnerMP Hi Michael, chk out 'How effective are common medications: a perspective based on meta-analyses of major drugs' h…
RT @pash22: Summary of effect sizes for common pharmacological treatments https://t.co/drslmnqNfj https://t.co/68oQMzjzRr
RT @Martin_Ploederl: Antidepressants vs. other pharmacological treatments. Note that the effect size for AD is in fact smaller than depic…
図1:一般的な薬物療法による効果の大きさ (#EffectSize) の要約。#標準化平均差 (#SMD) で表した。中央グラフは Cohen's d [ https://t.co/apLZ8ZxARP] の区分による色分け。 https://t.co/bTlVYQfPUT https://t.co/RmcEaiPQTo
一般的な薬はどれくらい有効か:主要な薬物のメタ解析に基づく視点 2015/10 結論:薬効に関してより現実的になる必要があると感じる。医師は、全ての患者が薬剤に反応し、#プラセボ には反応しないと信じるかもしれないが、多くの疾患が #自然寛解 〜 https://t.co/AF6h3b6RWn https://t.co/zvMZedGlBW
Antidepressants vs. other pharmacological treatments. Note that the effect size for AD is in fact smaller than depicted: according to new studies, d = 0.3 or ~ 50% responder (vs. ~ 40% responder for placebo).
@HengartnerMP Hi Michael, chk out 'How effective are common medications: a perspective based on meta-analyses of major drugs' https://t.co/AXvuOvuI7u via @StefanLeucht et al
RT @pash22: Summary of effect sizes for common pharmacological treatments https://t.co/drslmnqNfj https://t.co/68oQMzjzRr