Title |
Batch correction of microarray data substantially improves the identification of genes differentially expressed in Rheumatoid Arthritis and Osteoarthritis
|
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Published in |
BMC Medical Genomics, June 2012
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DOI | 10.1186/1755-8794-5-23 |
Pubmed ID | |
Authors |
Peter Kupfer, Reinhard Guthke, Dirk Pohlers, Rene Huber, Dirk Koczan, Raimund W Kinne |
Abstract |
Batch effects due to sample preparation or array variation (type, charge, and/or platform) may influence the results of microarray experiments and thus mask and/or confound true biological differences. Of the published approaches for batch correction, the algorithm "Combating Batch Effects When Combining Batches of Gene Expression Microarray Data" (ComBat) appears to be most suitable for small sample sizes and multiple batches. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 1 | 1% |
United Kingdom | 1 | 1% |
New Zealand | 1 | 1% |
Argentina | 1 | 1% |
Denmark | 1 | 1% |
Unknown | 70 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 24% |
Student > Ph. D. Student | 14 | 19% |
Student > Master | 11 | 15% |
Student > Doctoral Student | 5 | 7% |
Student > Bachelor | 5 | 7% |
Other | 8 | 11% |
Unknown | 14 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 20 | 27% |
Agricultural and Biological Sciences | 13 | 17% |
Medicine and Dentistry | 10 | 13% |
Immunology and Microbiology | 4 | 5% |
Computer Science | 2 | 3% |
Other | 8 | 11% |
Unknown | 18 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2012.
All research outputs
#15,245,883
of 22,668,244 outputs
Outputs from BMC Medical Genomics
#671
of 1,211 outputs
Outputs of similar age
#106,303
of 166,794 outputs
Outputs of similar age from BMC Medical Genomics
#13
of 20 outputs
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