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Hepatitis C virus E2 protein involve in insulin resistance through an impairment of Akt/PKB and GSK3β signaling in hepatocytes

Overview of attention for article published in BMC Gastroenterology, June 2012
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Mentioned by

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2 tweeters

Citations

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11 Dimensions

Readers on

mendeley
16 Mendeley
Title
Hepatitis C virus E2 protein involve in insulin resistance through an impairment of Akt/PKB and GSK3β signaling in hepatocytes
Published in
BMC Gastroenterology, June 2012
DOI 10.1186/1471-230x-12-74
Pubmed ID
Authors

Ming-Ju Hsieh, Kuang-Ping Lan, Hao-Yu Liu, Xiao-Zong Zhang, Yaw-Feng Lin, Tzy-Yen Chen, Hui-Ling Chiou

Abstract

Hepatitis C virus (HCV) infection may cause liver diseases of various severities ranging from primary acute infection to life-threatening diseases, such as cirrhosis or hepatocellular carcinoma with poor prognosis. According to clinical findings, HCV infection may also lead to some extra-hepatic symptoms, including type 2 diabetes mellitus (DM). Since insulin resistance is the major etiology for type 2 DM and numerous evidences showed that HCV infection associated with insulin resistance, the involvement of E2 in the pathogenesis of type 2 DM and underlying mechanisms were investigated in this study.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 6%
Brazil 1 6%
Japan 1 6%
Unknown 13 81%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 31%
Student > Ph. D. Student 4 25%
Student > Bachelor 2 13%
Student > Postgraduate 1 6%
Student > Master 1 6%
Other 3 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 38%
Unspecified 3 19%
Medicine and Dentistry 3 19%
Immunology and Microbiology 2 13%
Biochemistry, Genetics and Molecular Biology 2 13%
Other 0 0%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 June 2012.
All research outputs
#7,141,600
of 12,373,180 outputs
Outputs from BMC Gastroenterology
#327
of 800 outputs
Outputs of similar age
#59,897
of 120,008 outputs
Outputs of similar age from BMC Gastroenterology
#1
of 1 outputs
Altmetric has tracked 12,373,180 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 800 research outputs from this source. They receive a mean Attention Score of 4.5. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 120,008 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them