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Huntington's Disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database

Overview of attention for article published in BMC Neurology, June 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

blogs
1 blog
twitter
9 tweeters

Citations

dimensions_citation
29 Dimensions

Readers on

mendeley
59 Mendeley
Title
Huntington's Disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database
Published in
BMC Neurology, June 2012
DOI 10.1186/1471-2377-12-47
Pubmed ID
Authors

Ravi Kiran Reddy Kalathur, Miguel A Hernández-Prieto, Matthias E Futschik

Abstract

Huntington's disease (HD) is a fatal progressive neurodegenerative disorder caused by the expansion of the polyglutamine repeat region in the huntingtin gene. Although the disease is triggered by the mutation of a single gene, intensive research has linked numerous other genes to its pathogenesis. To obtain a systematic overview of these genes, which may serve as therapeutic targets, CHDI Foundation has recently established the HD Research Crossroads database. With currently over 800 cataloged genes, this web-based resource constitutes the most extensive curation of genes relevant to HD. It provides us with an unprecedented opportunity to survey molecular mechanisms involved in HD in a holistic manner.

Twitter Demographics

The data shown below were collected from the profiles of 9 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 5%
United Kingdom 1 2%
Portugal 1 2%
Australia 1 2%
Unknown 53 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 29%
Student > Ph. D. Student 9 15%
Student > Master 9 15%
Student > Bachelor 9 15%
Other 6 10%
Other 8 14%
Unknown 1 2%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 37%
Medicine and Dentistry 13 22%
Biochemistry, Genetics and Molecular Biology 6 10%
Neuroscience 5 8%
Chemistry 2 3%
Other 7 12%
Unknown 4 7%

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2012.
All research outputs
#911,272
of 12,373,815 outputs
Outputs from BMC Neurology
#94
of 1,406 outputs
Outputs of similar age
#8,683
of 120,046 outputs
Outputs of similar age from BMC Neurology
#2
of 25 outputs
Altmetric has tracked 12,373,815 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,406 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 120,046 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.