Title |
Protocol for the PACE trial: A randomised controlled trial of adaptive pacing, cognitive behaviour therapy, and graded exercise as supplements to standardised specialist medical care versus standardised specialist medical care alone for patients with the chronic fatigue syndrome/myalgic encephalomyelitis or encephalopathy
|
---|---|
Published in |
BMC Neurology, March 2007
|
DOI | 10.1186/1471-2377-7-6 |
Pubmed ID | |
Authors |
Peter D White, Michael C Sharpe, Trudie Chalder, Julia C DeCesare, Rebecca Walwyn |
Abstract |
Chronic fatigue syndrome (CFS, also called myalgic encephalomyelitis /encephalopathy or ME) is a debilitating condition with no known cause or cure. Improvement may occur with medical care and additional therapies of pacing, cognitive behavioural therapy and graded exercise therapy. The latter two therapies have been found to be efficacious in small trials, but patient organisations surveys have reported adverse effects. Although pacing has been advocated by patient organisations, it lacks empirical support. Specialist medical care is commonly provided but its efficacy when given alone is not established. This trial compares the efficacy of the additional therapies when added to specialist medical care against specialist medical care alone. |
Twitter Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 33 | 33% |
United States | 4 | 4% |
Australia | 3 | 3% |
Netherlands | 3 | 3% |
Norway | 2 | 2% |
Belgium | 1 | <1% |
Lithuania | 1 | <1% |
Sweden | 1 | <1% |
Mexico | 1 | <1% |
Other | 6 | 6% |
Unknown | 46 | 46% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 86 | 85% |
Practitioners (doctors, other healthcare professionals) | 9 | 9% |
Scientists | 4 | 4% |
Science communicators (journalists, bloggers, editors) | 1 | <1% |
Unknown | 1 | <1% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 1% |
Spain | 1 | <1% |
United States | 1 | <1% |
Vietnam | 1 | <1% |
Unknown | 187 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 34 | 18% |
Researcher | 31 | 16% |
Student > Ph. D. Student | 27 | 14% |
Student > Bachelor | 17 | 9% |
Student > Doctoral Student | 14 | 7% |
Other | 42 | 22% |
Unknown | 27 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 49 | 26% |
Medicine and Dentistry | 41 | 21% |
Nursing and Health Professions | 19 | 10% |
Sports and Recreations | 8 | 4% |
Agricultural and Biological Sciences | 6 | 3% |
Other | 31 | 16% |
Unknown | 38 | 20% |