| Title |
Glucagon-like peptide-1 analogs against antipsychotic-induced weight gain: potential physiological benefits
|
|---|---|
| Published in |
BMC Medicine, August 2012
|
| DOI | 10.1186/1741-7015-10-92 |
| Pubmed ID | |
| Authors |
Bjørn H Ebdrup, Filip K Knop, Pelle L Ishøy, Egill Rostrup, Birgitte Fagerlund, Henrik Lublin, Birte Glenthøj |
| Abstract |
Antipsychotic-induced weight gain constitutes a major unresolved clinical problem which may ultimately be associated with reducing life expectancy by 25 years. Overweight is associated with brain deterioration, cognitive decline and poor quality of life, factors which are already compromised in normal weight patients with schizophrenia.Here we outline the current strategies against antipsychotic-induced weight gain, and we describe peripheral and cerebral effects of the gut hormone glucagon-like peptide-1 (GLP-1). Moreover, we account for similarities in brain changes between schizophrenia and overweight patients. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 43% |
| Brazil | 1 | 14% |
| Denmark | 1 | 14% |
| Unknown | 2 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 43% |
| Scientists | 2 | 29% |
| Practitioners (doctors, other healthcare professionals) | 2 | 29% |
Mendeley readers
The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Denmark | 1 | 1% |
| Australia | 1 | 1% |
| Unknown | 78 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 16% |
| Researcher | 11 | 13% |
| Student > Postgraduate | 10 | 12% |
| Student > Master | 10 | 12% |
| Student > Bachelor | 8 | 10% |
| Other | 14 | 17% |
| Unknown | 16 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 35% |
| Psychology | 11 | 13% |
| Neuroscience | 5 | 6% |
| Agricultural and Biological Sciences | 5 | 6% |
| Nursing and Health Professions | 2 | 2% |
| Other | 8 | 10% |
| Unknown | 22 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2020.
All research outputs
#3,068,831
of 25,654,806 outputs
Outputs from BMC Medicine
#1,908
of 4,067 outputs
Outputs of similar age
#20,330
of 186,639 outputs
Outputs of similar age from BMC Medicine
#25
of 47 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,067 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.9. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 186,639 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.