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A tissue biopsy-based epigenetic multiplex PCR assay for prostate cancer detection

Overview of attention for article published in BMC Urology, June 2012
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Mentioned by

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1 tweeter
facebook
1 Facebook page

Citations

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30 Dimensions

Readers on

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46 Mendeley
Title
A tissue biopsy-based epigenetic multiplex PCR assay for prostate cancer detection
Published in
BMC Urology, June 2012
DOI 10.1186/1471-2490-12-16
Pubmed ID
Authors

Leander Van Neste, Joseph Bigley, Adam Toll, Gaëtan Otto, James Clark, Paul Delrée, Wim Van Criekinge, Jonathan I Epstein

Abstract

PSA-directed prostate cancer screening leads to a high rate of false positive identifications and an unnecessary biopsy burden. Epigenetic biomarkers have proven useful, exhibiting frequent and abundant inactivation of tumor suppressor genes through such mechanisms. An epigenetic, multiplex PCR test for prostate cancer diagnosis could provide physicians with better tools to help their patients. Biomarkers like GSTP1, APC and RASSF1 have demonstrated involvement with prostate cancer, with the latter two genes playing prominent roles in the field effect. The epigenetic states of these genes can be used to assess the likelihood of cancer presence or absence.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 7%
Hong Kong 1 2%
United Kingdom 1 2%
Canada 1 2%
Unknown 40 87%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 22%
Student > Ph. D. Student 6 13%
Student > Bachelor 6 13%
Student > Master 5 11%
Other 4 9%
Other 10 22%
Unknown 5 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 30%
Medicine and Dentistry 14 30%
Biochemistry, Genetics and Molecular Biology 7 15%
Engineering 4 9%
Unknown 7 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 August 2012.
All research outputs
#9,535,568
of 12,410,450 outputs
Outputs from BMC Urology
#198
of 306 outputs
Outputs of similar age
#84,743
of 124,996 outputs
Outputs of similar age from BMC Urology
#3
of 5 outputs
Altmetric has tracked 12,410,450 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 306 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 124,996 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.