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Stat3 is a positive regulator of gap junctional intercellular communication in cultured, human lung carcinoma cells

Overview of attention for article published in BMC Cancer, December 2012
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Title
Stat3 is a positive regulator of gap junctional intercellular communication in cultured, human lung carcinoma cells
Published in
BMC Cancer, December 2012
DOI 10.1186/1471-2407-12-605
Pubmed ID
Authors

Mulu Geletu, Rozanne Arulanandam, Samantha Greer, Aaron Trotman-Grant, Evangelia Tomai, Leda Raptis

Abstract

Neoplastic transformation of cultured cells by a number of oncogenes such as src suppresses gap junctional, intercellular communication (GJIC); however, the role of Src and its effector Signal transducer and activator of transcription-3 (Stat3) upon GJIC in non small cell lung cancer (NSCLC) has not been defined. Immunohistochemical analysis revealed high Src activity in NSCLC biopsy samples compared to normal tissues. Here we explored the potential effect of Src and Stat3 upon GJIC, by assessing the levels of tyr418-phosphorylated Src and tyr705-phosphorylated Stat3, respectively, in a panel of NSCLC cell lines.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 8%
United States 1 8%
Unknown 11 85%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 31%
Professor > Associate Professor 3 23%
Student > Bachelor 1 8%
Student > Doctoral Student 1 8%
Professor 1 8%
Other 2 15%
Unknown 1 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 38%
Biochemistry, Genetics and Molecular Biology 2 15%
Pharmacology, Toxicology and Pharmaceutical Science 2 15%
Medicine and Dentistry 2 15%
Unknown 2 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2012.
All research outputs
#3,078,440
of 4,507,211 outputs
Outputs from BMC Cancer
#1,524
of 2,430 outputs
Outputs of similar age
#192,518
of 282,686 outputs
Outputs of similar age from BMC Cancer
#68
of 112 outputs
Altmetric has tracked 4,507,211 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,430 research outputs from this source. They receive a mean Attention Score of 2.4. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
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We're also able to compare this research output to 112 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.