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The prevalence of drug resistance among treatment-naïve HIV-1-infected individuals in China during pre- and post- 2004

Overview of attention for article published in BMC Infectious Diseases, October 2016
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Mentioned by

twitter
4 tweeters

Citations

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4 Dimensions

Readers on

mendeley
10 Mendeley
Title
The prevalence of drug resistance among treatment-naïve HIV-1-infected individuals in China during pre- and post- 2004
Published in
BMC Infectious Diseases, October 2016
DOI 10.1186/s12879-016-1928-x
Pubmed ID
Authors

Hanping Li, Shuai Chang, Yang Han, Daomin Zhuang, Lin Li, Yongjian Liu, Siyang Liu, Zuoyi Bao, Wenfu Zhang, Hongbin Song, Taisheng Li, Jingyun Li

Abstract

The widespread use of antiretroviral therapies has led to considerable concerns about the prevalence of drug-resistant, as transmission of drug-resistant (TDR) strains poses a challenge for the control of the HIV-1 epidemic. We conducted an epidemiological study enrolling treatment-naïve HIV-1-positive subjects at the Peking Union Medical College Hospital since 1991. Drug resistance was determined by submitting the sequences to the Stanford University Network HIV-1 database. Of 521 participants, 478 samples were amplified and sequenced successfully. HIV Transmitted drug resistance prevalence in China was determined to be 6.7 %. We did not find significant differences in the TDR rate by demographic characteristics. No significant time trend in the prevalence of overall TDR was observed (p > 0.05). We identified an intermediate prevalence of transmitted drug resistance (TDR), exhibiting a stable time trend. These findings enhance our understanding of HIV-1 drug resistance prevalence and time trend, and provide some guidelines for the comprehensive public health strategy of TDR prevention.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 40%
Researcher 3 30%
Unspecified 2 20%
Other 1 10%
Readers by discipline Count As %
Unspecified 3 30%
Medicine and Dentistry 2 20%
Immunology and Microbiology 2 20%
Agricultural and Biological Sciences 1 10%
Social Sciences 1 10%
Other 1 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 May 2017.
All research outputs
#7,729,032
of 12,819,002 outputs
Outputs from BMC Infectious Diseases
#2,384
of 4,746 outputs
Outputs of similar age
#149,624
of 285,919 outputs
Outputs of similar age from BMC Infectious Diseases
#278
of 576 outputs
Altmetric has tracked 12,819,002 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,746 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 285,919 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 576 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.