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The association between interleukin-28B gene polymorphisms as a potential biomarker and the risk of chronic Periodontitis in an Iranian population

Overview of attention for article published in Head & Face Medicine, June 2017
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  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

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1 tweeter
googleplus
1 Google+ user

Citations

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3 Dimensions

Readers on

mendeley
9 Mendeley
Title
The association between interleukin-28B gene polymorphisms as a potential biomarker and the risk of chronic Periodontitis in an Iranian population
Published in
Head & Face Medicine, June 2017
DOI 10.1186/s13005-017-0148-y
Pubmed ID
Authors

Zahra Heidari, Bita Moudi, Hamidreza Mahmoudzadeh-Sagheb, Mehrnoosh Moudi

Abstract

Chronic Periodontitis (CP) is a common inflammatory disease affects supporting tissues of the teeth and can lead to tooth loss. The objective of this study was to determine the relationship between polymorphisms in the IL-28B gene and chronic periodontitis in an Iranian population. Two hundred and ten CP patients and one hundred healthy subjects were enrolled in the present case-control study. The rs12979860 and rs8099917 SNPs were identified using RFLP and T-ARMS-PCR methods respectively. SNP analysis revealed that the G allele of rs8099917 SNP and T allele of rs12979860 SNP increased susceptibility to CP compared to the A allele and C allele (p < 0.0001, OR = 2.712, CI = 1.783-4.126; p < 0.0001, OR = 2.538, CI = 1.784-3.613 respectively). In addition, the CT/GT, TT/GG and TT/GT haplotypes were predominant in CP patients and significantly associated with the increased risk of CP. IL-28B polymorphisms may be useful predictive factors for chronic periodontitis and correlated to the susceptibility to CP infection in our population.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 2 22%
Researcher 2 22%
Student > Postgraduate 2 22%
Student > Ph. D. Student 1 11%
Student > Master 1 11%
Other 1 11%
Readers by discipline Count As %
Medicine and Dentistry 6 67%
Nursing and Health Professions 1 11%
Unspecified 1 11%
Engineering 1 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 August 2017.
All research outputs
#6,656,249
of 11,626,228 outputs
Outputs from Head & Face Medicine
#55
of 228 outputs
Outputs of similar age
#127,437
of 262,998 outputs
Outputs of similar age from Head & Face Medicine
#2
of 6 outputs
Altmetric has tracked 11,626,228 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 228 research outputs from this source. They receive a mean Attention Score of 1.6. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,998 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.