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Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer’s disease Drosophila models

Overview of attention for article published in BMC Complementary and Alternative Medicine, March 2014
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Mentioned by

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3 tweeters

Citations

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29 Dimensions

Readers on

mendeley
57 Mendeley
Title
Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer’s disease Drosophila models
Published in
BMC Complementary and Alternative Medicine, March 2014
DOI 10.1186/1472-6882-14-88
Pubmed ID
Authors

Xue Wang, Jun-Ran Kim, Seong-Baek Lee, Young-Joon Kim, Moon Young Jung, Hyung-Wook Kwon, Young-Joon Ahn

Abstract

Alzheimer's disease (AD) is the most common type of presenile and senile dementia. The human β-amyloid precursor cleavage enzyme (BACE-1) is a key enzyme responsible for amyloid plaque production, which implicates the progress and symptoms of AD. Here we assessed the anti-BACE-1 and behavioral activities of curcuminoids from rhizomes of Curcuma longa (Zingiberaceae), diarylalkyls curcumin (CCN), demethoxycurcumin (DMCCN), and bisdemethoxycurcumin (BDMCCN) against AD Drosophila melanogaster models.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 2%
Japan 1 2%
Unknown 55 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 15 26%
Student > Ph. D. Student 9 16%
Unspecified 7 12%
Student > Master 5 9%
Researcher 5 9%
Other 15 26%
Unknown 1 2%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 23%
Medicine and Dentistry 13 23%
Unspecified 10 18%
Pharmacology, Toxicology and Pharmaceutical Science 5 9%
Nursing and Health Professions 4 7%
Other 11 19%
Unknown 1 2%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2015.
All research outputs
#9,508,733
of 12,373,386 outputs
Outputs from BMC Complementary and Alternative Medicine
#1,587
of 2,512 outputs
Outputs of similar age
#122,408
of 193,906 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#6
of 9 outputs
Altmetric has tracked 12,373,386 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,512 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 193,906 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.