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Presence of the full-length KIR2DS4 gene reduces the chance of rheumatoid arthritis patients to respond to methotrexate treatment

Overview of attention for article published in BMC Musculoskeletal Disorders, July 2014
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Title
Presence of the full-length KIR2DS4 gene reduces the chance of rheumatoid arthritis patients to respond to methotrexate treatment
Published in
BMC Musculoskeletal Disorders, July 2014
DOI 10.1186/1471-2474-15-256
Pubmed ID
Authors

Edyta Majorczyk, Andrzej Pawlik, Daria Gendosz, Piotr Kuśnierczyk

Abstract

KIR genes coding for natural killer cell immunoglobulin-like receptors, KIR, influence the effector and regulatory function of NK cells as well as some subpopulations of T lymphocytes (e.g. CD4+CD28-KIR+) depending on presence of ligands (particularly HLA-C molecules). KIR-KIR ligand interaction may lead to the development of autoimmune disorders, including rheumatoid arthritis (RA). However, their role in the response of RA patients to methotrexate therapy is not known.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
Poland 1 4%
Singapore 1 4%
Unknown 25 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 21%
Researcher 5 18%
Unspecified 4 14%
Student > Master 3 11%
Other 3 11%
Other 7 25%
Readers by discipline Count As %
Medicine and Dentistry 6 21%
Agricultural and Biological Sciences 6 21%
Unspecified 5 18%
Biochemistry, Genetics and Molecular Biology 4 14%
Immunology and Microbiology 3 11%
Other 4 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 August 2014.
All research outputs
#3,033,767
of 4,508,925 outputs
Outputs from BMC Musculoskeletal Disorders
#1,299
of 1,534 outputs
Outputs of similar age
#74,063
of 113,513 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#104
of 112 outputs
Altmetric has tracked 4,508,925 research outputs across all sources so far. This one is in the 20th percentile – i.e., 20% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,534 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 113,513 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 112 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.