Title |
Safety and effectiveness of a Patient Blood Management (PBM) program in surgical patients - the study design for a multi-centre prospective epidemiologic non-inferiority trial
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Published in |
BMC Health Services Research, November 2014
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DOI | 10.1186/s12913-014-0576-3 |
Pubmed ID | |
Authors |
Patrick Meybohm, Dania Patricia Fischer, Christof Geisen, Markus Matthias Miller, Christian Friedrich Weber, Eva Herrmann, Bjirn Steffen, Erhard Seifried, Kai Zacharowski, the German PBM Study Core Group |
Abstract |
Preoperative and hospital-acquired anaemia is common among surgical patients. It is associated with an increased risk of morbidity and mortality and a strong risk factor for allogeneic blood transfusions with their own inherent risks. Patient Blood Management (PBM) concepts aim to increase and preserve autologous erythrocyte volume and to optimise haemotherapy. They thus have great potential to benefit patients. This prospective, multi-centre clinical trial tests the hypothesis that PBM programs are safe and effective in the care of adult surgical patients. Primary outcome is a composite endpoint of adverse events and in-hospital mortality. This trial will determine whether the implementation of a PBM program is safe and effective in terms of clinical outcome compared to a pre-implementation cohort. This trial is registered at www.clinicaltrials.gov (NCT01820949). |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 38 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 18% |
Other | 4 | 11% |
Student > Master | 4 | 11% |
Student > Bachelor | 3 | 8% |
Student > Doctoral Student | 2 | 5% |
Other | 7 | 18% |
Unknown | 11 | 29% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 15 | 39% |
Nursing and Health Professions | 5 | 13% |
Business, Management and Accounting | 2 | 5% |
Social Sciences | 1 | 3% |
Unspecified | 1 | 3% |
Other | 0 | 0% |
Unknown | 14 | 37% |