@TijlDeBie 2/n En dan heb ik het nog niet over de confounders die zowel verband houden met je keuze om je al dan niet te vaccineren als deze die verband houden met het risico op besmetting. Ref. (beiden in tempore non suspecto) : https://t.co/jOxCzfTQlm e
test-negative desingて,1-オッズ比でVE(%)を単純に計算しているけど,rare disease assumptionを満たしていなくてもいいのかな?と思ったら,この場合のオッズ比は真のリスク比を計算していることになるので,大丈夫らしい,というのがへぇーと思いました。 https://t.co/wrkDMb0UiK
@Ziggy10thSlough @DrAseemMalhotra This result was based on a test-negative case controlled study, and for triple jabbed only had 2 weeks of data. See here for how such trials are biased if vaccination influences the decision to seek medical care due to red
@Ribeyeslaps @_merightnow @nypost Dude even nejm says they’re using this (faulty) method of estimating effectiveness, but it takes a brain a bit bigger than walnut to figure out: https://t.co/OPiqUR5Dcm Be careful or we can expose all of these phony eff
@RolandHartz @SJallamion @ordre_medecins Il faut lire le lien ci dessous, je pense que remettre en cause une méthodologie en disant que je me trompe... ce n'est pas dire que "je" me trompe, mais que beaucoup de scientifiques se trompent. . https://t.co/gK
RT @Karl_MD: No desenho com teste negativo (TN), apenas os pacientes que procuraram um serviço médico com alguma sintomatologia relacionada…
RT @Karl_MD: No desenho com teste negativo (TN), apenas os pacientes que procuraram um serviço médico com alguma sintomatologia relacionada…
No desenho com teste negativo (TN), apenas os pacientes que procuraram um serviço médico com alguma sintomatologia relacionada à Covid E que testaram negativo, são usados como controle. https://t.co/15qJKSfwAK
@humptacles @BorderReiverReb @PamLongCO Test-negative, case control study design. Used with other vaccines to determine effectiveness. Feel free to read about it. https://t.co/EnSNxNTHhs
So what is vaccine effectiveness & how do you know? 5 people w/Moderna vaccine got COVID 95 people w/Saltwater placebo got virus a proportional reduction in disease btwn participants who were vaccinated and control participants https://t.co/RH7xogD
@deralteGaukler @PriyankaPulla In my humble / personal opinion, the "test-negative" design that is used for influenza effectiveness might be a good place to start. It does have some limitations, and there are some good reviews on the topic such as this - h
A comparison of the test-negative and the traditional case-control study designs for estimation of... https://t.co/VvkwBooe3K #bmcinfectdis