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Poly herbal formulation with anti-elastase and anti-oxidant properties for skin anti-aging

Overview of attention for article published in BMC Complementary and Alternative Medicine, January 2018
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Title
Poly herbal formulation with anti-elastase and anti-oxidant properties for skin anti-aging
Published in
BMC Complementary and Alternative Medicine, January 2018
DOI 10.1186/s12906-018-2097-9
Pubmed ID
Authors

Induja Kalyana Sundaram, Deepika Deeptirekha Sarangi, Vignesh Sundararajan, Shinomol George, Sahabudeen Sheik Mohideen

Abstract

Skin forms an important part of human innate immune system. Wrinkles, thinning and roughening of skin are some of the symptoms that affect the skin as it ages. Reactive oxygen species induced oxidative stress plays a major role in skin aging by modulating the elastase enzyme level in the skin. Extrinsic factors that affect skin aging such as UV radiation can also cause malignant melanoma. Here we selected four medicinal plant materials, namely, leaves of Nyctanthes arbor-tristis, unripe and ripe Aegle marmelos fruit pulp and the terminal meristem of Musa paradisiaca flower and investigated their anti-aging properties and cytotoxicity in vitro individually as well as in a poly herbal formulation containing the four plant extracts in different ratios. The phytochemical contents of the plant extracts were investigated for radical scavenging activity and total reducing power. Based upon its anti-oxidant properties, a poly herbal formulation containing leaves of Nyctanthes arbor-tristis, unripe and ripe fruit pulp of Aegle marmelos, and the terminal meristem of Musa paradisiaca flower in the ratio 6:2:1:1 (Poly Herbal Formulation 1) and 1:1:1:1 (Poly Herbal Formulation 2), respectively were formulated. It has been observed that the Poly Herbal Formulation 1 was more potent than Poly Herbal Formulation 2 due to better anti-oxidant and anti-elastase activities in NIH3T3 fibroblast cells. In addition Poly Herbal formulation 1 also had better anti-cancer activity in human malignant melanoma cells. Based on these results these beneficial plant extracts were identified for its potential application as an anti-aging agent in skin creams as well as an anti-proliferation compound against cancer cells.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 9 33%
Student > Bachelor 7 26%
Other 2 7%
Student > Doctoral Student 2 7%
Student > Master 2 7%
Other 5 19%
Readers by discipline Count As %
Unspecified 9 33%
Agricultural and Biological Sciences 6 22%
Pharmacology, Toxicology and Pharmaceutical Science 6 22%
Biochemistry, Genetics and Molecular Biology 2 7%
Nursing and Health Professions 1 4%
Other 3 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2018.
All research outputs
#10,411,340
of 13,055,200 outputs
Outputs from BMC Complementary and Alternative Medicine
#1,813
of 2,626 outputs
Outputs of similar age
#250,735
of 346,408 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#1
of 1 outputs
Altmetric has tracked 13,055,200 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,626 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 346,408 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them