RT @andersgranholm: #MethodMonday 30: Adaptive trials #2 - adaptive platform trials https://t.co/7NWQvDH96F https://t.co/nepiY6gYyB https:/…
RT @andersgranholm: #MethodMonday 30: Adaptive trials #2 - adaptive platform trials https://t.co/7NWQvDH96F https://t.co/nepiY6gYyB https:/…
RT @andersgranholm: #MethodMonday 30: Adaptive trials #2 - adaptive platform trials https://t.co/7NWQvDH96F https://t.co/nepiY6gYyB https:/…
RT @andersgranholm: #MethodMonday 30: Adaptive trials #2 - adaptive platform trials https://t.co/7NWQvDH96F https://t.co/nepiY6gYyB https:/…
#MethodMonday 30: Adaptive trials #2 - adaptive platform trials https://t.co/7NWQvDH96F https://t.co/nepiY6gYyB https://t.co/MrBTdEFOyT This week's articles extend last week's theme on adaptive trials (https://t.co/dVqTXyB2iX) to adaptive platform trials
'Adaptive designs in clinical trials: why use them, and how to run and report them' via @thomas_jaki et al
RT @SofiaSVillar1: This paper was an outcome of the adaptive designs working group 🙌 @thomas_jaki @JMSWason @MRCNIHRTMRP and many others
This paper was an outcome of the adaptive designs working group 🙌 @thomas_jaki @JMSWason @MRCNIHRTMRP and many others
RT @andersgranholm: #MethodMonday 29: Adaptive trials #1 - introduction and overview https://t.co/bEVvuItZCX This week's excellent article…
RT @andersgranholm: #MethodMonday 29: Adaptive trials #1 - introduction and overview https://t.co/bEVvuItZCX This week's excellent article…
#MethodMonday 29: Adaptive trials #1 - introduction and overview https://t.co/bEVvuItZCX This week's excellent article is an intro to adaptive clinical trials, i.e., trials that use interim/adaptive analyses to modify the course of the trial. 1/..
RT @CollJamie: @JasonKimAF @ArthritisFdn @david_felson a lot of people at #OARSI2023 brought up adaptive trials, but you need early markers…
@JasonKimAF @ArthritisFdn @david_felson a lot of people at #OARSI2023 brought up adaptive trials, but you need early markers of treatment response to know whether/how you should adapt/change your trial. Great overview of adaptive designs here: https://t.c
Finally, some nice overview papers to read 🔴https://t.co/twir1f7OkM 🟡https://t.co/XvbC2mDY5h 🟢https://t.co/xjFar1RBGs #ASR23 https://t.co/8eJg1CtWcL
@HoertelN @AngryCardio After observational studies and instead of traditional RCTs, why not launch more often adaptative design RCTs, "described as ‘planning to be flexible’,‘driving with one’s eyes open’"? Do you know if studies of that kind were conducte
Adaptive designs can make CT +flexible by utilising results [collected] in the trial to modify [its] course in accordance with pre-specified rules. Trials w/ adaptive design are often +efficient, informative, ethical than trials w/ a trad. fixed design htt
Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/YDv2kVzjEN Master Protocols to Study Multiple Therapies, Multiple Diseases, or Both https://t.co/2hJtX30sHp
This tutorial paper from 2018 provides guidance on key aspects of adaptive designs that are relevant to clinical trialists. https://t.co/lY7ZqY09Vl
Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/5Ux7Pv8gAL
RT @MRC_BSU: (1/2) Did you want to learn about #AdaptiveDesigns for #ICTD2021? Here is the first of two non-technical introductions: https:…
RT @MRC_BSU: (1/2) Did you want to learn about #AdaptiveDesigns for #ICTD2021? Here is the first of two non-technical introductions: https:…
RT @MRC_BSU: (1/2) Did you want to learn about #AdaptiveDesigns for #ICTD2021? Here is the first of two non-technical introductions: https:…
RT @MRC_BSU: (1/2) Did you want to learn about #AdaptiveDesigns for #ICTD2021? Here is the first of two non-technical introductions: https:…
RT @MRC_BSU: (1/2) Did you want to learn about #AdaptiveDesigns for #ICTD2021? Here is the first of two non-technical introductions: https:…
(1/2) Did you want to learn about #AdaptiveDesigns for #ICTD2021? Here is the first of two non-technical introductions: https://t.co/yTHuwrqjuu
RT @mchapmanonline: Prof David Currow discusses the importance of adaptive design in difficult to recruit studies such as many in #palliati…
RT @meera_agar: @DavidCurrow adaptive designs - how can that help symptom trials? https://t.co/UVuzEHZ2Qa #paccsccstforum2021
RT @meera_agar: @DavidCurrow adaptive designs - how can that help symptom trials? https://t.co/UVuzEHZ2Qa #paccsccstforum2021
RT @meera_agar: @DavidCurrow adaptive designs - how can that help symptom trials? https://t.co/UVuzEHZ2Qa #paccsccstforum2021
RT @mchapmanonline: Prof David Currow discusses the importance of adaptive design in difficult to recruit studies such as many in #palliati…
RT @mchapmanonline: Prof David Currow discusses the importance of adaptive design in difficult to recruit studies such as many in #palliati…
RT @meera_agar: @DavidCurrow adaptive designs - how can that help symptom trials? https://t.co/UVuzEHZ2Qa #paccsccstforum2021
RT @meera_agar: @DavidCurrow adaptive designs - how can that help symptom trials? https://t.co/UVuzEHZ2Qa #paccsccstforum2021
RT @mchapmanonline: Prof David Currow discusses the importance of adaptive design in difficult to recruit studies such as many in #palliati…
@DavidCurrow adaptive designs - how can that help symptom trials? https://t.co/UVuzEHZ2Qa #paccsccstforum2021
Prof David Currow discusses the importance of adaptive design in difficult to recruit studies such as many in #palliativecare trials #paccsccst2021. Provided this reference @pa_ccsc @UTS_CST https://t.co/Z8CUoiThqn
Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/6kujL6g824
RT @MRCNIHRTMRP: How to correctly interpret and report results of an adaptive trial? Look no further! Read about all of this and more in ou…
RT @MRCNIHRTMRP: How to correctly interpret and report results of an adaptive trial? Look no further! Read about all of this and more in ou…
RT @MRCNIHRTMRP: How to correctly interpret and report results of an adaptive trial? Look no further! Read about all of this and more in ou…
RT @MRCNIHRTMRP: How to correctly interpret and report results of an adaptive trial? Look no further! Read about all of this and more in ou…
RT @MRCNIHRTMRP: How to correctly interpret and report results of an adaptive trial? Look no further! Read about all of this and more in ou…
RT @MRCNIHRTMRP: How to correctly interpret and report results of an adaptive trial? Look no further! Read about all of this and more in ou…
RT @MRCNIHRTMRP: How to correctly interpret and report results of an adaptive trial? Look no further! Read about all of this and more in ou…
How to correctly interpret and report results of an adaptive trial? Look no further! Read about all of this and more in our tutorial paper lead by Philip Pallmann @CTRCardiffUni: https://t.co/c2SnuX2pME
RT @mdimairo: Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/jLpDWIDlQw
Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/jLpDWIDlQw
RT @kaz_yos: Adaptive designs in clinical trials: why use them, and how to run and report them | BMC Medicine | Full Text https://t.co/dsRo…
Adaptive designs in clinical trials: why use them, and how to run and report them | BMC Medicine | Full Text https://t.co/dsRo0bGxfX
Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/n5rTtFkUqB
And this one as well. https://t.co/5Ux7Pv8gAL
RT @mdimairo: 6/n In addition, the nature of research questions we can answer using this fixed approach is very limited. To address this, a…
6/n In addition, the nature of research questions we can answer using this fixed approach is very limited. To address this, adaptive designs are a useful alternative in our toolbox. I recommend this easy-to-read paper on this topic https://t.co/5Ux7Pv8gAL
RT @avkwong: Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/dt8M68aXta #covid19 #covidmarat…
RT @avkwong: The future of research? Randomised Embedded Multi-factorial Adaptive Platform Trial @remap_cap #COVID19 #COVIDmarathon ht…
RT @avkwong: Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/dt8M68aXta #covid19 #covidmarat…
RT @avkwong: Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/dt8M68aXta #covid19 #covidmarat…
RT @avkwong: Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/dt8M68aXta #covid19 #covidmarat…
The future of research? Randomised Embedded Multi-factorial Adaptive Platform Trial @remap_cap #COVID19 #COVIDmarathon https://t.co/dt8M68aXta
RT @avkwong: Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/dt8M68aXta #covid19 #covidmarat…
Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/dt8M68aXta #covid19 #covidmarathon https://t.co/HHcipzlyeC
@kazakhelo @Nermbed I do not know what happened in this trial per se.. But recently this paradigm has been challenged especially for new drugs and biologics...do you have a link to remedisevir trial already so we can critically appraise it? https://t.co/B
Very interesting that the WHO Solidarity Trial is using Adaptive Design https://t.co/sbUkY58VSc
RT @GilliesKatie: @smithhazelann @statsepi @hrbtmrn @shauntreweek @sarah_d_birch admittedly I don’t know a lot about response adaptive rand…
@smithhazelann @statsepi @hrbtmrn @shauntreweek @sarah_d_birch admittedly I don’t know a lot about response adaptive randomisation. @thomas_jaki is one of the UK experts on Adaptive design trials (of which RAR is one type) & co-wrote this neat piece wh
RT @balajis: Adaptive clinical trials are one way to formalize this intuition. Basically, streaming data continuously back from the trial i…
RT @balajis: Adaptive clinical trials are one way to formalize this intuition. Basically, streaming data continuously back from the trial i…
RT @balajis: Adaptive clinical trials are one way to formalize this intuition. Basically, streaming data continuously back from the trial i…
RT @balajis: Adaptive clinical trials are one way to formalize this intuition. Basically, streaming data continuously back from the trial i…
Adaptive clinical trials are one way to formalize this intuition. Basically, streaming data continuously back from the trial in structured form to permit iteration & reduce cost in time and money. https://t.co/2HEl7u2q3b https://t.co/5cbycTqNp4
RT @JamillaHussain1: Clinicians/clinical academics interested in what the hell an #adaptive #design #trial is-this is a great paper, pitche…
RT @JamillaHussain1: Clinicians/clinical academics interested in what the hell an #adaptive #design #trial is-this is a great paper, pitche…
RT @JamillaHussain1: Clinicians/clinical academics interested in what the hell an #adaptive #design #trial is-this is a great paper, pitche…
Clinicians/clinical academics interested in what the hell an #adaptive #design #trial is-this is a great paper, pitched perfectly for us numpties without (I presume...) being too dumbed down @DrGWheeler @BMCMedicine https://t.co/XrJrSbuFUJ #hpm_methods
@BradCutrellMD Perhaps adaptive clinical trials be of benefit here? https://t.co/fgWEStsBeq
#adativedesigns in Clinical Trials #RCTs @BioMedCentral https://t.co/74u331iZc6
RT @mdimairo: Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/5Ux7Pv8gAL
RT @mdimairo: Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/5Ux7Pv8gAL
RT @mdimairo: Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/5Ux7Pv8gAL
Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/5Ux7Pv8gAL
RT @hswapnil: Many more types, discussed here https://t.co/K5skTDgecA #KIDNEYCon https://t.co/9Pr8kj0sTp
Many more types, discussed here https://t.co/K5skTDgecA #KIDNEYCon https://t.co/9Pr8kj0sTp
RT @Wagner_Nephro: Adaptive designs in clinical trials: why use them, and how to run and report them —Dr. Swapnil Hiremath Swapnil @hswapni…
Adaptive designs in clinical trials: why use them, and how to run and report them —Dr. Swapnil Hiremath Swapnil @hswapnil, MD, MPH, The Ottawa Hospital 🇨🇦 #KidneyCon #Nephrology #MedTwitter #NephTwitter #FOAMed https://t.co/NFZNG6fdXu
@Corey_Yanofsky As you know, there's a great deal of work in how to deal w/ adaptive trials while yielding error probs that reflect the capability of the method to avoid mistaken interpretation. (Even those w/ Bayesian elements.) A first link in looking it
@aidybarnett It depends on how this was done. There are some designs which actually allow one to increase sample size if the standard error of measurement is higher than expected (e.g. the CARISA trial https://t.co/XIL1k0Lx37). This should be done in a bl
RT @CTRU_Sheffield: A recent BMC Medicine publication could be of interest to those interested in adaptive trials. This is in collaboration…
RT @mdimairo: You may be interested in our published paper on "Adaptive designs in clinical trials: why use them, and how to run and report…
Adaptive designs in clinical trials: why use them, and how to run and report them. https://t.co/2cAC0idZic
Adaptive #designs in #ClinicalTrials : why use them, and how to run and #report them https://t.co/vBhBUDPLVe #clinicaltrialsday #ICTD2018 https://t.co/OWGDM2IWLe
RT @mdimairo: Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/5Ux7Pv8gAL
Adaptive designs in clinical trials: why use them, and how to run and report them https://t.co/5Ux7Pv8gAL
RT @VR_Cornelius: This really is a lovely paper introducing the utility of adaptive designs - references, case examples and practical advic…
RT @MRCCTU: Publication - Adaptive designs in #clinicaltrials why use them, and how to run and report them https://t.co/8mDPJY7y52 https://…
RT @MRCCTU: Publication - Adaptive designs in #clinicaltrials why use them, and how to run and report them https://t.co/8mDPJY7y52 https://…
Publication - Adaptive designs in #clinicaltrials why use them, and how to run and report them https://t.co/8mDPJY7y52 https://t.co/ilRdkCePQx
RT @MRCCTU: Publication - Adaptive designs in #clinicaltrials why use them, and how to run and report them https://t.co/8mDPJY7y52 https://…
RT @MRCCTU: Publication - Adaptive designs in #clinicaltrials why use them, and how to run and report them https://t.co/8mDPJY7y52 https://…
RT @MRCCTU: Publication - Adaptive designs in #clinicaltrials why use them, and how to run and report them https://t.co/8mDPJY7y52 https://…