@LogarithmicDis @RetractionWatch @HHS_ORI Maybe @RetractionWatch should ask @HHS_ORI the same question and post the answer? And maybe also ask some major research centres? It's bizarre that this is so widespread but there is no clarity about what institut
#5yrsago Despite public pledges, leading scientific journals still allow statistical misconduct and refuse to correct it https://t.co/941o56gtJa #5yrsago Yacht dealers rely on Instagram “yacht influencers” to flip their wares https://t.co/rb40L38ab8 7/ h
@hannahsbee One of the things I teach my students about open science is that journals often don't want to know if something contradicts what they've been publishing already - this isn't limited to sex/gender issues. Thanks to @DermotLynott and @bengoldacr
RT @jamesheathers: @jgitchell @ConscienHealth @dsquintana @lonnibesancon @GidMK @StuartJRitchie @JonBaronforMD Well, you know the old clini…
RT @jamesheathers: @jgitchell @ConscienHealth @dsquintana @lonnibesancon @GidMK @StuartJRitchie @JonBaronforMD Well, you know the old clini…
@jgitchell @ConscienHealth @dsquintana @lonnibesancon @GidMK @StuartJRitchie @JonBaronforMD Well, you know the old clinical trial registration motto: "pre-register your obvious p-hacking, get caught, suffer absolutely no consequences whatsoever" https:/
@MathieuMolimard @OJBoyau @ansm @SFPT_fr @afpfr @sup_recherche @Sante_Gouv @justice_gouv @APMinfos Changer la stratégie d'analyse ... un grand Ø en méthodologie Totalement interdit. = du niveau "changement des critères de jugement " poke @bengoldacre cf ht
RT @mlrethlefsen: #Metascience2023 talk on post-publication critique in journals reminds me greatly of the COMPAare study, which was a stun…
RT @mlrethlefsen: #Metascience2023 talk on post-publication critique in journals reminds me greatly of the COMPAare study, which was a stun…
RT @mlrethlefsen: #Metascience2023 talk on post-publication critique in journals reminds me greatly of the COMPAare study, which was a stun…
RT @mlrethlefsen: #Metascience2023 talk on post-publication critique in journals reminds me greatly of the COMPAare study, which was a stun…
#Metascience2023 talk on post-publication critique in journals reminds me greatly of the COMPAare study, which was a stunning piece of work: https://t.co/GYgOE7ckXF
RT @TheSGEM: This informs my skepticism of studies, even if they follow CONSORT and are published in high impact journals. Post-publicatio…
RT @TheSGEM: This informs my skepticism of studies, even if they follow CONSORT and are published in high impact journals. Post-publicatio…
This informs my skepticism of studies, even if they follow CONSORT and are published in high impact journals. Post-publication peer review is an important part of science. https://t.co/SRCr9coiQo @First10EM @KirstyChallen @srrezaie @stemlyns @CCREM2 @CADT
Calling out bad science https://t.co/2GYD81jGTr #badscience
3/ @bengoldacre has published so many great papers on this topic, and issues in clinical research in general. Too many great ones to list, so I will just share this one here: https://t.co/w8gLsHc8TD
Looking at tons of trials, it's pretty clear selective outcome reporting and outcome switching remain massive problems and I'm not sure anyone who can do anything about it cares. See: https://t.co/MKG8fSYEFN and https://t.co/AKAFWkJIP5
@wilshica @_Lucibee @richardvallee @davidtuller1 @ssppeerroo @Healthy_Control @b_m_hughes @cochranecollab @C0PE @CochraneLibrary @NICEComms @Columbia @TomKindlon Yes, and I am not disputing that your re-analysis using the original protocol was valid. It's
@davidtuller1 @Healthy_Control @b_m_hughes @cochranecollab @C0PE @CochraneLibrary @NICEComms Well, that is certainly interesting. Did you do a piece on that? Might be worth one at some point. You could include a comment on the Goldacre reference I highligh
@Bertrandization @hildabast @TheAtlantic Yes. Sadly the bait-and-switch of prespecified protocol outcomes in clinical trials is extremely common. @Bengoldacre tried to make a big deal out of it (https://t.co/eVJyOQBW5t). Notably, some "top" journals were s
COMPare: un estudio prospectivo de cohortes que corrige y monitorea 58 ensayos mal reportados en tiempo real | Ensayos | Texto Completo https://t.co/0HxGEfwUXb
From Danielle Wenner, ""Almost every trial" pubbed in 5 high-impact med journals over a 6-week period had engaged in outcome switching. The authors sent correction letters to the journals & most were rejected https://t.co/h4OdiSbgrV #bioethics #researc
"In this house we believe that Science Is Real ..." https://t.co/h4OdiSbgrV
@learnfromerror @richarddmorey @stephensenn 18/ Lastly, just wanted to point out some lessons from medicine we definitely shouldn't pass up when creating infrastructures in other fields. https://t.co/OkYQWSi4bw
@AndrewPGrieve I guess the point was, that having pregistered a thing, by itself, doesn't necessarily lead to 2. or 3. and you can do 2. and 3. with other tools than public preregistration. But you of course know all this; maybe it's just wordings https:
RT @bengoldacre: RIGHT I must get back to work (writing scientific papers). If anyone is feeling dewy eyed about peer review, please read o…
RT @bengoldacre: RIGHT I must get back to work (writing scientific papers). If anyone is feeling dewy eyed about peer review, please read o…
RIGHT I must get back to work (writing scientific papers). If anyone is feeling dewy eyed about peer review, please read our papers on how editors reacted when we tried to correct 58 misreported, peer reviewed, clinical trials. https://t.co/Dzfl1hJ37t ht
RT @bengoldacre: @COMPare_Trials We sent correction letters on every misreported clinical trial in the world's biggest medical journals, to…
Reviewers of every other field with more recent pre-registration demands, need to check the pre-registration... Lest they'll find themselves in the outcome switching hell where medicine is today. 2/2 https://t.co/wcNlCbRcxH
Academia is increasingly an information oligarchy Now measures taken to contain the replication crisis are routinely ignored by those purporting to adopt them. https://t.co/wG3syvxFMT (Exactly the same thing happens in reg review) #DoAsISayNotAsIDo
RT @westwoodsam1: #10 COMPare: a prospective cohort study correcting and monitoring 58 misreported trials “...journals listed as endorsing…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
They found "We found high levels of outcome misreporting amongst the five top medical journals listed as endorsing the CONSORT" So using Diamond Princess stats only 13 in 3750 died of who 11 are over 70. Fake expert news only 6 in 10,000 die So lets rest
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @MartinFierro769: 19/n Henry Drysdale du CEBM d'Oxford, interviewé par le Washington Post avait publié avec @bengoldacre une étude qui m…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
Remdesivir trials were subjected to outcome-switching, invalidating the trial and flagged by @bengoldacre earlier today. Phenomenon investigated by Ben over a year ago https://t.co/f2wvj2N4e6
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
I'll just leave this here 'k?
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
RT @bengoldacre: Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our…
Since that covid trial with the outcome switch has everyone excited about outcome switching in clinical trials: here's our (definitive) study on what happens when you try to correct undisclosed outcome misreporting in academic papers that breach guidelines
19/n Henry Drysdale du CEBM d'Oxford, interviewé par le Washington Post avait publié avec @bengoldacre une étude qui montrait à quel point les essais cliniques publiés par de grandes revues médicales étaient défectueux et biaisés https://t.co/Zv3XK9HxFX ht
@radiokeller @JasonConnorPhD If primary outcome is changed *after* one sees data, then one can decide which outcome to use based on what gives most favorable results. Needs to be blinded to preserve integrity. https://t.co/2aijSBzfDl
#10 COMPare: a prospective cohort study correcting and monitoring 58 misreported trials “...journals listed as endorsing CONSORT, which require complete outcome reporting, fail to ensure compliance...majority of correction letters were rejected.” 🤦♂️ ht
RT @Musicaypaz501: @lopez_briz @EmilioAlegre1 Lack of publication and publication bias of RCTs as problems to deal with before judging othe…
@Medtorek @BlancaUsoz ¿Qué evidencia? ¿Se ha leído este mini-hilo? Imposible, no le ha dado tiempo. Prejuicios sin juicio. No lo digo tampoco por nadie en especial...https://t.co/U8AR8oTueV
@Medtorek @BlancaUsoz Copio pequeño hilo que acabo de publicar. AUTOCRITICA, por favor.https://t.co/U8AR8oTueV
RT @Musicaypaz501: @lopez_briz @EmilioAlegre1 Lack of publication and publication bias of RCTs as problems to deal with before judging othe…
@lopez_briz @EmilioAlegre1 Lack of publication and publication bias of RCTs as problems to deal with before judging other sources of evidence ... https://t.co/fnNEpVvfDD https://t.co/NRebrVhwXQ https://t.co/ozWA6Kqxrp
RT @HengartnerMP: @f_hieronymus The scandal is that reporting biases and spin are still commonplace. De Vries et al have updated the Turner…
@f_hieronymus The scandal is that reporting biases and spin are still commonplace. De Vries et al have updated the Turner et al analysis from 2008 to include the most recent antidepressants, and the problems prevail https://t.co/4GD4vCgs6h See also Goldacr
RT @HengartnerMP: @f_hieronymus It has improved after 2007. But very recent work, like that of Dr Goldacre clearly shows that the problem i…
RT @HengartnerMP: @f_hieronymus It has improved after 2007. But very recent work, like that of Dr Goldacre clearly shows that the problem i…
RT @HengartnerMP: @f_hieronymus It has improved after 2007. But very recent work, like that of Dr Goldacre clearly shows that the problem i…
RT @HengartnerMP: @f_hieronymus It has improved after 2007. But very recent work, like that of Dr Goldacre clearly shows that the problem i…
@f_hieronymus It has improved after 2007. But very recent work, like that of Dr Goldacre clearly shows that the problem is still very prevalent. See: https://t.co/2ulJmWW2D1 https://t.co/9iroc9d06x
RT @realsci_DE: @bengoldacre Er und sein Team verglichen 67 publizierte Trials mit den preregistrierten Protokollen. In 87% der Fälle fande…
RT @realsci_DE: @bengoldacre Er und sein Team verglichen 67 publizierte Trials mit den preregistrierten Protokollen. In 87% der Fälle fande…