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Combined analgesics in (headache) pain therapy: shotgun approach or precise multi-target therapeutics?

Overview of attention for article published in BMC Neurology, March 2011
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77 Mendeley
Title
Combined analgesics in (headache) pain therapy: shotgun approach or precise multi-target therapeutics?
Published in
BMC Neurology, March 2011
DOI 10.1186/1471-2377-11-43
Pubmed ID
Authors

Andreas Straube, Bernhard Aicher, Bernd L Fiebich, Gunther Haag

Abstract

Pain in general and headache in particular are characterized by a change in activity in brain areas involved in pain processing. The therapeutic challenge is to identify drugs with molecular targets that restore the healthy state, resulting in meaningful pain relief or even freedom from pain. Different aspects of pain perception, i.e. sensory and affective components, also explain why there is not just one single target structure for therapeutic approaches to pain. A network of brain areas ("pain matrix") are involved in pain perception and pain control. This diversification of the pain system explains why a wide range of molecularly different substances can be used in the treatment of different pain states and why in recent years more and more studies have described a superior efficacy of a precise multi-target combination therapy compared to therapy with monotherapeutics.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Turkey 2 3%
Chile 1 1%
Malaysia 1 1%
Nepal 1 1%
Australia 1 1%
Brazil 1 1%
Venezuela, Bolivarian Republic of 1 1%
United States 1 1%
Unknown 68 88%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 22%
Student > Bachelor 11 14%
Researcher 10 13%
Other 8 10%
Student > Master 7 9%
Other 18 23%
Unknown 6 8%
Readers by discipline Count As %
Medicine and Dentistry 26 34%
Agricultural and Biological Sciences 11 14%
Pharmacology, Toxicology and Pharmaceutical Science 7 9%
Neuroscience 4 5%
Engineering 3 4%
Other 19 25%
Unknown 7 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 April 2012.
All research outputs
#3,083,802
of 4,506,977 outputs
Outputs from BMC Neurology
#648
of 900 outputs
Outputs of similar age
#47,497
of 76,757 outputs
Outputs of similar age from BMC Neurology
#18
of 19 outputs
Altmetric has tracked 4,506,977 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 900 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
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We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.