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Hornerin, an S100 family protein, is functional in breast cells and aberrantly expressed in breast cancer

Overview of attention for article published in BMC Cancer, June 2012
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Title
Hornerin, an S100 family protein, is functional in breast cells and aberrantly expressed in breast cancer
Published in
BMC Cancer, June 2012
DOI 10.1186/1471-2407-12-266
Pubmed ID
Authors

Jodie M Fleming, Erika Ginsburg, Shannon D Oliver, Paul Goldsmith, Barbara K Vonderhaar

Abstract

Recent evidence suggests an emerging role for S100 protein in breast cancer and tumor progression. These ubiquitous proteins are involved in numerous normal and pathological cell functions including inflammatory and immune responses, Ca(2+) homeostasis, the dynamics of cytoskeleton constituents, as well as cell proliferation, differentiation, and death. Our previous proteomic analysis demonstrated the presence of hornerin, an S100 family member, in breast tissue and extracellular matrix. Hornerin has been reported in healthy skin as well as psoriatic and regenerating skin after wound healing, suggesting a role in inflammatory/immune response or proliferation. In the present study we investigated hornerin's potential role in normal breast cells and breast cancer.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Belgium 1 3%
Unknown 34 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 33%
Student > Master 9 25%
Researcher 6 17%
Student > Bachelor 3 8%
Professor > Associate Professor 3 8%
Other 3 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 36%
Medicine and Dentistry 11 31%
Biochemistry, Genetics and Molecular Biology 5 14%
Engineering 3 8%
Economics, Econometrics and Finance 1 3%
Other 3 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2012.
All research outputs
#9,905,805
of 12,372,945 outputs
Outputs from BMC Cancer
#3,021
of 4,558 outputs
Outputs of similar age
#86,160
of 120,505 outputs
Outputs of similar age from BMC Cancer
#1
of 2 outputs
Altmetric has tracked 12,372,945 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,558 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 120,505 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them