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Alterations of leptin in the course of inflammation and severe sepsis

Overview of attention for article published in BMC Infectious Diseases, September 2012
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1 tweeter

Citations

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Readers on

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48 Mendeley
Title
Alterations of leptin in the course of inflammation and severe sepsis
Published in
BMC Infectious Diseases, September 2012
DOI 10.1186/1471-2334-12-217
Pubmed ID
Authors

Michael Behnes, Martina Brueckmann, Siegfried Lang, Christian Putensen, Joachim Saur, Martin Borggrefe, Ursula Hoffmann

Abstract

The adipokine leptin regulates energy expenditure, vascular function, bone and cartilage growth as well as the immune system and systemic inflammatory response. Several activating effects towards T cells, monocytes, endothelium cells and cytokine production have been reported suggesting a protective role of leptin in the setting of an acute systemic inflammation. However, the pathophysiological role of leptin during severe sepsis is currently not elucidated in detail. This study aims to investigate leptin expression in cultured human adipocytes within an inflammatory model and in patients suffering from severe sepsis and evaluates treatment effects of drotrecogin alpha (activated) (DAA), the recombinant form of human activated protein C.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 19%
Student > Ph. D. Student 7 15%
Professor > Associate Professor 4 8%
Student > Master 4 8%
Student > Doctoral Student 3 6%
Other 9 19%
Unknown 12 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 25%
Medicine and Dentistry 11 23%
Pharmacology, Toxicology and Pharmaceutical Science 3 6%
Nursing and Health Professions 3 6%
Immunology and Microbiology 2 4%
Other 4 8%
Unknown 13 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2012.
All research outputs
#20,166,700
of 22,678,224 outputs
Outputs from BMC Infectious Diseases
#6,423
of 7,642 outputs
Outputs of similar age
#150,315
of 168,685 outputs
Outputs of similar age from BMC Infectious Diseases
#81
of 105 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,642 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,685 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.