2,139 followers
Recently, @dagmareh showed that blocking proteolysis at this site makes HTT a better substrate for autophagy & repairs the autophagy pathway overall. https://t.co/oOP0ijXfcB
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Looking forward to reading this. When @dagmareh & I did this in Huntington disease mice, we saw that the disease causing protein was significantly reduced in their brains after 1 week. But mice eat what you give them. So more research is needed. http
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RT @biorxiv_pubd: Feeding Schedule And Proteolysis Regulate Autophagic Clearance Of Mutant Huntingtin published as: https://t.co/LsxjB7aeS4…
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Feeding Schedule And Proteolysis Regulate Autophagic Clearance Of Mutant Huntingtin published as: https://t.co/LsxjB7aeS4 #Acta_Neuropathologica_Communications #biorxiv
2,139 followers
RT @B_A_Benitez: Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease. https…
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Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease. https://t.co/3ZSuMCmYjZ
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RT @DrDDOM: This is an excellent blog about our work lead by @dagmareh on how we used diet & #autophagy to reduce mutant huntingtin in mous…
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RT @DrDDOM: This is an excellent blog about our work lead by @dagmareh on how we used diet & #autophagy to reduce mutant huntingtin in mous…
1,129 followers
RT @DrDDOM: This is an excellent blog about our work lead by @dagmareh on how we used diet & #autophagy to reduce mutant huntingtin in mous…
2,139 followers
This is an excellent blog about our work lead by @dagmareh on how we used diet & #autophagy to reduce mutant huntingtin in mouse brains & why we think another mouse model is resistant to HD. Here's the original work. https://t.co/w8L68Lzczg #huntin
2,139 followers
RT @NeurologyToday: Strict intermittent fasting that promotes autophagy leads to significantly lowers levels of mutant huntintin protein in…
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RT @DrDDOM: Our paper led by @dagmareh shows fasting induced autophagy reduces mutant huntingtin in #Huntingtonsdisease mouse models & sugg…
83 followers
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RT @CAN_ACN: Research by Michael Hayden's team @UBC shows strict eating schedule can lower Huntington disease protein in mice https://t.co/…
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RT @CAN_ACN: Research by Michael Hayden's team @UBC shows strict eating schedule can lower Huntington disease protein in mice https://t.co/…
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RT @CAN_ACN: Research by Michael Hayden's team @UBC shows strict eating schedule can lower Huntington disease protein in mice https://t.co/…
888 followers
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Research by Michael Hayden's team @UBC shows strict eating schedule can lower Huntington disease protein in mice https://t.co/nTojAl1PyS Paper in @ActaNeuropathol https://t.co/e0pwDz6b0I
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RT @ActaNeuropathol: Fasting and scheduled feeding decreases mutant huntingtin in a #HuntingtonDisease model via promoting #autophagy, prov…
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RT @DrDDOM: ICYMI: our recent study published at @actaneuropathol comm (https://t.co/w8L68LhBHI) led by @dagmareh was highlighted by @Neuro…
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ICYMI: our recent study published at @actaneuropathol comm (https://t.co/w8L68LhBHI) led by @dagmareh was highlighted by @NeuroscienceNew & others. Strict Eating Schedule Can Lower Huntington’s Protein: Mouse Study https://t.co/HVfu5ajl6H https://t.co/
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Preventing mutant huntingtin proteolysis (mHTT) and intermittent fasting promote autophagy in models of Huntington disease https://t.co/6T6ugX8Cgc Via @BioMedCentral
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RT @ActaNeuropathol: Fasting and scheduled feeding decreases mutant huntingtin in a #HuntingtonDisease model via promoting #autophagy, prov…
4,147 followers
RT @ActaNeuropathol: Fasting and scheduled feeding decreases mutant huntingtin in a #HuntingtonDisease model via promoting #autophagy, prov…
2,139 followers
RT @ActaNeuropathol: Fasting and scheduled feeding decreases mutant huntingtin in a #HuntingtonDisease model via promoting #autophagy, prov…
175 followers
RT @ActaNeuropathol: Fasting and scheduled feeding decreases mutant huntingtin in a #HuntingtonDisease model via promoting #autophagy, prov…
1,532 followers
RT @ActaNeuropathol: Fasting and scheduled feeding decreases mutant huntingtin in a #HuntingtonDisease model via promoting #autophagy, prov…
2,139 followers
RT @recherche_anima: #Huntington: pour stimuler l'autophagie contre l'accumulation de la protéine #huntingtine, il suffit de #jeûner voire…
1,247 followers
RT @recherche_anima: #Huntington: pour stimuler l'autophagie contre l'accumulation de la protéine #huntingtine, il suffit de #jeûner voire…
2,578 followers
RT @AutophagyPapers: Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease. h…
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RT @drjasonfung: Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington di... https://…
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RT @AutophagyPapers: Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease. h…
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#Huntington: pour stimuler l'autophagie contre l'accumulation de la protéine #huntingtine, il suffit de #jeûner voire manger à des heures fixes... du moins chez la #souris https://t.co/uS2XckfVDu https://t.co/0j8lfzNgO9
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RT @AutophagyPapers: Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease. h…
1,608 followers
Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease. https://t.co/MgPQSIoaNw https://t.co/yNDStHh6LX
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RT @drjasonfung: Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington di... https://…
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This article is a bit technical for me. Given T2D sometimes accompanies Huntington’s, do you think metabolic dysfunction triggers Huntington’s ? Possibly through elevated insulin preventing autophagy ? https://t.co/NkHQwn7COw
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@DMRegister Lost medical privileges when had dementia patient fast as form of prayer. Considered it "eating disorder". Has been called type 3 diabetes What do you think @drjasonfung https://t.co/3aFDdS2SmH
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RT @drjasonfung: Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington di... https://…
1,792 followers
RT @drjasonfung: Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington di... https://…
1,933 followers
RT @drjasonfung: Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington di... https://…
3,608 followers
RT @drjasonfung: Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington di... https://…
2,139 followers
RT @drjasonfung: Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington di... https://…
199,361 followers
Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington di... https://t.co/ruoPwyHXHr
512 followers
RT @NeurologyToday: Strict intermittent fasting that promotes autophagy leads to significantly lowers levels of mutant huntintin protein in…
1,626 followers
RT @NeurologyToday: Strict intermittent fasting that promotes autophagy leads to significantly lowers levels of mutant huntintin protein in…
3,433 followers
980 followers
Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease https://t.co/XGEht2w8Pd
849 followers
RT @NeurologyToday: Strict intermittent fasting that promotes autophagy leads to significantly lowers levels of mutant huntintin protein in…
7 followers
RT @NeurologyToday: Strict intermittent fasting that promotes autophagy leads to significantly lowers levels of mutant huntintin protein in…
63,600 followers
Strict intermittent fasting that promotes autophagy leads to significantly lowers levels of mutant huntintin protein in the brain, finds mouse study. #Huntingtondisease https://t.co/CSd7itejG8 Read about other advances in HD here: https://t.co/xnDKYTHOTD
888 followers
RT @dagmareh: Happy to see this published! Great working together with @DrDDOM @mandeliz9 @SafiaLadha @Nskotte @Bettyyennguyen and others @…
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@dagmareh @DrDDOM Congrats! https://t.co/vQsHEfpum5
2,299 followers
RT @DrDDOM: Our paper led by @dagmareh shows fasting induced autophagy reduces mutant huntingtin in #Huntingtonsdisease mouse models & sugg…
83 followers
RT @dagmareh: Happy to see this published! Great working together with @DrDDOM @mandeliz9 @SafiaLadha @Nskotte @Bettyyennguyen and others @…
2,872 followers
RT @DrDDOM: Our paper led by @dagmareh shows fasting induced autophagy reduces mutant huntingtin in #Huntingtonsdisease mouse models & sugg…
2,139 followers
RT @dagmareh: Happy to see this published! Great working together with @DrDDOM @mandeliz9 @SafiaLadha @Nskotte @Bettyyennguyen and others @…
175 followers
RT @DrDDOM: Our paper led by @dagmareh shows fasting induced autophagy reduces mutant huntingtin in #Huntingtonsdisease mouse models & sugg…
2,139 followers
Our paper led by @dagmareh shows fasting induced autophagy reduces mutant huntingtin in #Huntingtonsdisease mouse models & suggests protective effect of proteolysis resistant form of HTT is better substrate 4 autophagy .@EurekAlert https://t.co/XiePD7T
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RT @DrDDOM: Happy to see this published as well. Long time in the making. Among other things, we show that fasting induced autophagy can re…
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Happy to see this published as well. Long time in the making. Among other things, we show that fasting induced autophagy can reduce mutant huntingtin in the brains of an #huntingtonsdisease mouse model. Up https://t.co/csd18laXHs
849 followers
RT @dagmareh: Happy to see this published! Great working together with @DrDDOM @mandeliz9 @SafiaLadha @Nskotte @Bettyyennguyen and others @…
175 followers
Happy to see this published! Great working together with @DrDDOM @mandeliz9 @SafiaLadha @Nskotte @Bettyyennguyen and others @CMMT_UBC! Mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington di... https://t.co/dsaLh